Evidence map›Paper›PMID 36639404›Full record

ArticleScientific reports2023

Pulmonary function three to five months after hospital discharge for COVID-19: a single centre cohort study.

Tina Krueger, Janelle van den Heuvel, Vivian van Kampen-van den Boogaart, Roel van Zeeland, D Jannet Mehagnoul-Schipper, Dennis G Barten, Lieve Knarren, Arno F G Maas, Caroline E Wyers, Debbie Gach and 4 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
5.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

  1. Recovery of lung function during the first year after COVID-19: a systematic review and meta-analysis.European respiratory review : an official journal of the European Respiratory Society · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 1 country.

Tina KruegerDepartment of Clinical Epidemiology, VieCuri Medical Centre, Venlo, The Netherlands.
Janelle van den HeuvelDepartment of Clinical Epidemiology, VieCuri Medical Centre, Venlo, The Netherlands.
Vivian van Kampen-van den BoogaartDepartment of Pulmonology, VieCuri Medical Centre, Venlo, The Netherlands.
Roel van ZeelandDepartment of Pulmonology, VieCuri Medical Centre, Venlo, The Netherlands.
D Jannet Mehagnoul-SchipperDepartment of Intensive Care, VieCuri Medical Centre, Venlo, The Netherlands.
Dennis G BartenDepartment of Emergency Medicine, VieCuri Medical Centre, Venlo, The Netherlands.
Lieve KnarrenDepartment of Internal Medicine, VieCuri Medical Centre, Venlo, The Netherlands.
Arno F G MaasDepartment of Internal Medicine, VieCuri Medical Centre, Venlo, The Netherlands.
Caroline E WyersDepartment of Internal Medicine, VieCuri Medical Centre, Venlo, The Netherlands.
Debbie GachDepartment of Clinical Epidemiology, VieCuri Medical Centre, Venlo, The Netherlands.
Annemie M W J ScholsDepartment of Respiratory Medicine, NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University Medical Centre+, Maastricht, The Netherlands.
Rosanne J H C G BeijersDepartment of Respiratory Medicine, NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University Medical Centre+, Maastricht, The Netherlands.
Joop P van den BerghDepartment of Internal Medicine, VieCuri Medical Centre, Venlo, The Netherlands.
Frits H M van OschDepartment of Clinical Epidemiology, VieCuri Medical Centre, Venlo, The Netherlands. fvosch@viecuri.nl.
VieCuri Medisch Centrum · NLMaastricht University Medical Centre · NLMaastricht University · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Some COVID-19 survivors suffer from persistent pulmonary function impairment, but the extent and associated factors are unclear. This study aimed to characterize pulmonary function impairment three to five months after hospital discharge and the association with disease severity. Survivors of COVID-19 after hospitalization to the VieCuri Medical Centre between February and December 2020 were invited for follow-up, three to five months after discharge. Dynamic and static lung volumes, respiratory muscle strength and diffusion capacity were measured. The cohort comprised 257 patients after a moderate (n = 33), severe (n = 151) or critical (n = 73) COVID-19 infection with a median follow-up of 112 days (interquartile range 96-134 days). The main sequelae included reduced diffusion capacity (36%) and reduced maximal expiratory pressure (24%). Critically ill patients were more likely to have reduced diffusion capacity than moderate (OR 8.00, 95% CI 2.46-26.01) and severe cases (OR 3.74, 95% CI 1.88-7.44) and lower forced vital capacity (OR 3.29, 95% CI 1.20-9.06) compared to severe cases. Many COVID-19 survivors, especially after a critical disease course, showed pulmonary function sequelae, mainly DLCO impairments, three to five months after discharge. Monitoring is needed to investigate the persistence of these symptoms and the longer-term implications of the COVID-19 burden.

Indexed as

COVID-19Cohort StudiesFollow-Up StudiesHospitalsHumansLungPatient Discharge

Identifiers

PMID36639404
PMCPMC9839688
OpenAlexW4315866086

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.