Evidence map›Paper›PMID 36638583›Full record

ArticleInternational journal of medical informatics2023

Clinical research staff perceptions on a natural language processing-driven tool for eligibility prescreening: An iterative usability assessment.

Betina Idnay, Yilu Fang, Caitlin Dreisbach, Karen Marder, Chunhua Weng, Rebecca Schnall

Abstract read
In one paragraph

Article in International journal of medical informatics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Betina IdnayColumbia University, School of Nursing, New York, NY, USA; Columbia University, Department of Neurology, New York, NY, USA; Columbia University, Department of Biomedical Informatics, New York, NY, USA. Electronic address: bsi2102@cumc.columbia.edu.
Yilu FangColumbia University, Department of Biomedical Informatics, New York, NY, USA.
Caitlin DreisbachColumbia University, Data Science Institute, New York, NY, USA.
Karen MarderColumbia University, Department of Neurology, New York, NY, USA.
Chunhua WengColumbia University, Department of Biomedical Informatics, New York, NY, USA.
Rebecca SchnallColumbia University, School of Nursing, New York, NY, USA; Columbia University, Mailman School of Public Health, Department of Population and Family Health, New York, NY, USA.

Funding

Clinical and Translational Science AwardUL1TR001873 · NCATS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI REILLY, MUREDACH P · 2016 to 2025
$99.0M
Research Education CoreP30AG066462 · NIA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI SCOTT A SMALL · 2020 to 2026
$30.1M
Reducing Health Disparities Through Informatics - Genomics SupplementT32NR007969 · NINR · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI SUZANNE BAKKEN, Rebecca Schnall · 2002 to 2026
$7.9M
Bridging the Semantic Gap Between Research Eligibility Criteria and Clinical DataR01LM009886 · NLM · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI WENG, CHUNHUA · 2009 to 2020
$5.3M
Reaching Communities through the Design of Information Visualizations (ReDIVis) Toolbox to Address COVID-19 Vaccine Hesitancy and Uptake.P30NR016587 · NINR · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI BAKKEN, SUZANNE, SMALDONE, ARLENE M · 2016 to 2022
$4.3M
Translator Red Knowledge (TReK)OT2TR003434 · NCATS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI DUMONTIER, MICHEL, TA, CASEY NGHIA · 2020 to 2024
$2.3M
Mentoring and Research in Self-Management for Health Promotion and Disease PreventionK24NR018621 · NINR · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI SCHNALL, REBECCA · 2019 to 2022
$384k
Improving Eligibility Prescreening for Alzheimer's Disease and Related Dementias Clinical Trials with Natural Language ProcessingR36HS028752 · AHRQ · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI IDNAY, BETINA ROSS SALDUA · 2022 to 2022
$21k
AHRQ HHS R36 HS028752NCATS NIH HHS OT2 TR003434NCATS NIH HHS UL1 TR001873NIA NIH HHS P30 AG066462NINR NIH HHS K24 NR018621NINR NIH HHS P30 NR016587NINR NIH HHS T32 NR007969NLM NIH HHS R01 LM009886
6 · The paper itself

Abstract

backgroundParticipant recruitment is a barrier to successful clinical research. One strategy to improve recruitment is to conduct eligibility prescreening, a resource-intensive process where clinical research staff manually reviews electronic health records data to identify potentially eligible patients. Criteria2Query (C2Q) was developed to address this problem by capitalizing on natural language processing to generate queries to identify eligible participants from clinical databases semi-autonomously.

objectiveWe examined the clinical research staff's perceived usability of C2Q for clinical research eligibility prescreening.

methodsTwenty clinical research staff evaluated the usability of C2Q using a cognitive walkthrough with a think-aloud protocol and a Post-Study System Usability Questionnaire. On-screen activity and audio were recorded and transcribed. After every-five evaluators completed an evaluation, usability problems were rated by informatics experts and prioritized for system refinement. There were four iterations of system refinement based on the evaluation feedback. Guided by the Organizational Framework for Intuitive Human-computer Interaction, we performed a directed deductive content analysis of the verbatim transcriptions.

resultsEvaluators aged from 24 to 46 years old (33.8; SD: 7.32) demonstrated high computer literacy (6.36; SD:0.17); female (75 %), White (35 %), and clinical research coordinators (45 %). C2Q demonstrated high usability during the final cycle (2.26 out of 7 [lower scores are better], SD: 0.74). The number of unique usability issues decreased after each refinement. Fourteen subthemes emerged from three themes: seeking user goals, performing well-learned tasks, and determining what to do next.

conclusionsThe cognitive walkthrough with a think-aloud protocol informed iterative system refinement and demonstrated the usability of C2Q by clinical research staff. Key recommendations for system development and implementation include improving system intuitiveness and overall user experience through comprehensive consideration of user needs and requirements for task completion.

Indexed as

Natural Language ProcessingUser-Computer InterfaceAdultComputersElectronic Health RecordsFemaleHumansMiddle AgedRecordsYoung AdultClinical researchCognitive walkthroughCohort identificationEligibility prescreeningNatural language processingUsability

Identifiers

PMID36638583
PMCPMC9912278

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.