Evidence map›Paper›PMID 3663831›Full record

ArticleBiophysical journal1987

Molecular aggregation characterized by high order autocorrelation in fluorescence correlation spectroscopy.

A G Palmer, N L Thompson

Abstract read
In one paragraph

Article in Biophysical journal, 1987. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

55 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Label-Free Fluctuation Spectroscopy Based on Coherent Anti-Stokes Raman Scattering from Bulk Water Molecules.Chemphyschem : a European journal of chemical physics and physical chemistry · 2016
    Article
  12. Article
  13. Article
  14. Quantitation of ten 30S ribosomal assembly intermediates using fluorescence triple correlation spectroscopy.Proceedings of the National Academy of Sciences of the United States of America · 2012
    Article
  15. Article
  16. Review
  17. Article
  18. Lessons in fluctuation correlation spectroscopy.Annual review of physical chemistry · 2011
    Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

A G PalmerDepartment of Chemistry, University of North Carolina at Chapel Hill 27514.
N L Thompson

Funding

MOLECULAR DYNAMICS IN RECEPTOR-MEDIATED PHAGOCYTOSISR01GM037145 · NIGMS · UNIVERSITY OF NORTH CAROLINA CHAPEL HILL · PI THOMPSON, NANCY L. · 1986 to 1997
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CELL SURFACE DYNAMICS OF IGG FC RECEPTOR INTERACTIONSR55GM037145 · NIGMS · UNIVERSITY OF NORTH CAROLINA CHAPEL HILL · PI THOMPSON, NANCY L. · 1998 to 1998
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NIGMS NIH HHS GM-37145
6 · The paper itself

Abstract

The use of high order autocorrelation in fluorescence correlation spectroscopy for investigating aggregation in a sample that contains fluorescent molecules is described. Theoretical expressions for the fluorescence fluctuation autocorrelation functions defined by gm,n(tau) = [(delta fm(t + tau)delta fm(t] - (delta Fm(t] (delta Fn(t]]/(F)m+n, where delta F(t) is the fluorescence fluctuation at time t, (F) is the average fluorescence, and m and n are integers less than or equal to 3, are derived. Methods for determining the number densities and relative fluorescence yields of aggregates of different sizes from a series of Gm,n(0) values are outlined. The method is applied to 1,1'-dioctadecyl-3,3,3',3'-tetramethylindocarbocyanine perchlorate suspended in solutions of water and ethyl alcohol. The technique presented may prove useful in detecting and characterizing aggregates of fluorescent-labeled biological molecules such as cell surface receptors.

Indexed as

CarbocyaninesFluorescent DyesMacromolecular SubstancesModels, TheoreticalMolecular ConformationQuinolinesMathematicsSpectrometry, Fluorescence3,3'-dioctadecylindocarbocyanineCarbocyaninesFluorescent DyesMacromolecular SubstancesQuinolines

Identifiers

PMID3663831
PMCPMC1330077

What OpenQuestion holds

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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.