ArticleJornal brasileiro de nefrologia
Calcium carbide-ripened plantain induced alterations in plasma electrolytes concentration and kidney function in rats.
Article in Jornal brasileiro de nefrologia. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed, 8 citations in OpenAlex.
- Effects of Chemical Ripening With Calcium Carbide on Nutritional Composition, Antioxidant Capacity and Heavy Metal Accumulation in Climacteric Fruits.International journal of food science · 2026Article
- Fresh Pineapple Agronomy in the Republic of Benin: Recent Trends in Calcium Carbide Use and Producer Perceptions.Plant-environment interactions (Hoboken, N.J.) · 2025Article
- Study of food toxicology of toxins artificially introduced into the food or fruits.Toxicology research · 2023Article
- Substance used in the ripening of fruits can cause kidney damage and water and electrolytic disorders.Jornal brasileiro de nefrologiaArticle
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionArtificial fruit ripening agents such as ethanol, ethylene, ethephon, and calcium carbide (CaC2) is usually employed in stimulating the fruit ripening process. Currently, there is a paucity of information regarding the effects of various artificial fruits ripening methods on the health status of consumers. In this study, the physiological effects and possible health hazards associated with the consumption of plantain ripened by CaC2 and other non-chemical methods on the kidneys were investigated.
methodsArtificially ripened plantain was mixed with rat feed and fed to Wistar albino rats for four weeks, and the levels of plasma electrolytes (Na+, HCO3-, K+, and Cl-), urea, creatinine, as well as histological changes in the kidneys were determined.
resultsResults indicated that rats fed with carbide-ripened plantain had a significantly high level of plasma bicarbonate (HCO3-) compared to control rats., but there was no difference in the level of plasma sodium (Na+). However, the levels of plasma potassium (K+) and chloride (Cl-) were significantly low in rats fed with CaC2-ripened plantain as compared to the control rats. Furthermore, the levels of urea and creatinine were significantly high in rats fed with CaC2-ripened plantain compared to the control animals. Histological analyses showed glomeruli atrophy and tubular necrosis in kidneys of rats fed with CaC2-ripened plantain, thereby further indicating toxicity to the kidneys.
conclusionsHistological evidence and alterations in the level of the plasma electrolytes, urea, and creatinine suggest that consumption of fruits ripened with calcium carbide may be harmful to the kidneys.
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