Evidence map›Paper›PMID 36638145›Full record

ArticleJournal of feline medicine and surgery2023

Lymph node metastasis in feline cutaneous low-grade mast cell tumours.

Raphael Arz, Lavinia E Chiti, Christiane Krudewig, Valeria Grieco, Valeria Meier, Csilla Fejös, Damiano Stefanello, Mirja C Nolff

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of feline medicine and surgery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Raphael ArzClinic for Small Animal Surgery, Department for Small Animals, Vetsuisse Faculty, University of Zurich, Switzerland.ORCID 0000-0001-8894-5209
Lavinia E ChitiClinic for Small Animal Surgery, Department for Small Animals, Vetsuisse Faculty, University of Zurich, Switzerland.
Christiane KrudewigInstitute of Veterinary Pathology, Department for Small Animals, Vetsuisse Faculty, University of Zurich, Switzerland.ORCID 0000-0001-5894-6665
Valeria GriecoDepartment of Veterinary Medicine and Animal Science, University of Milan, Lodi, Italy.
Valeria MeierDivision of Radiation Oncology, Department for Small Animals, Vetsuisse Faculty, University of Zurich, Switzerland.ORCID 0000-0003-0793-9005
Csilla FejösDivision of Radiation Oncology, Department for Small Animals, Vetsuisse Faculty, University of Zurich, Switzerland.
Damiano StefanelloDepartment of Veterinary Medicine and Animal Science, University of Milan, Lodi, Italy.ORCID 0000-0003-2726-0366
Mirja C NolffClinic for Small Animal Surgery, Department for Small Animals, Vetsuisse Faculty, University of Zurich, Switzerland.ORCID 0000-0001-9317-7769
University of Zurich · CHUniversity of Milan · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThis retrospective study aimed to determine the incidence of nodal metastatic disease in cats affected by low-grade cutaneous mast cell tumours (MCTs) in our study population.

methodsThe clinical records of two centres were retrospectively searched for cats with cutaneous MCTs that had undergone lymphadenectomy of enlarged and non-enlarged lymph nodes. All primary tumours were histologically reviewed by two experienced pathologists and graded as high- or low-grade based on the grading system for feline cutaneous MCT. We graded the lymph nodes based on the grading scheme used for canine MCTs and considered HN2 and HN3 nodes to be metastatic. The number of patients with nodal metastasis was calculated.

resultsWe identified 17 cats with cutaneous MCT resection and concurrent lymphadenectomy. All 21 MCTs were graded as low grade and 30 nodes were removed, with 12 being considered early or overtly metastatic (HN2 or HN3, respectively). Based on nodal status, 10/17 (59%) cats were affected by nodal metastasis in our population. CONCLUSIONS AND RELEVANCE: In contrast to previous reports, high percentage of cats with cutaneous MCTs in which lymphadenectomy was performed were presented with metastatic lymph nodes. The clinical relevance of this finding and a potential benefit of lymphadenectomy must be determined in future studies.

Indexed as

Cat DiseasesDog DiseasesSkin NeoplasmsAnimalsCatsDogsLymphatic MetastasisLymph NodesMast CellsRetrospective StudiesFeline cutaneous mastocytosisnodal gradingnodal metastasis

Identifiers

PMID36638145
PMCPMC10812050
OpenAlexW4315927799

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.