Evidence map›Paper›PMID 36637747›Full record

ArticleMolecular neurobiology2023

Fear Conditioning Leads to Enduring Alterations in RNA Transcripts in Hippocampal Neuropil that are Dependent on EphB2 Forward Signaling.

Subhajit Jana, Monica Dines, Maya Lalzar, Raphael Lamprecht

Abstract read
PubMed Publisher
In one paragraph

Article in Molecular neurobiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Subhajit JanaSagol Department of Neurobiology, Faculty of Natural Sciences, University of Haifa, Haifa, Israel.
Monica DinesSagol Department of Neurobiology, Faculty of Natural Sciences, University of Haifa, Haifa, Israel.
Maya LalzarBioinformatics Service Unit, University of Haifa, Haifa, Israel.
Raphael LamprechtSagol Department of Neurobiology, Faculty of Natural Sciences, University of Haifa, Haifa, Israel. rlamp@research.haifa.ac.il.ORCID http://orcid.org/0000-0001-9701-5388
University of Haifa · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alterations in mRNA transcription have been associated with changes in brain functions. We wanted to examine if fear conditioning causes long-term changes in transcriptome profiles in the basolateral amygdala (BLA) and hippocampus using RNA-Seq and laser microdissection microscopy. We further aimed to uncover whether these changes are involved in memory formation by monitoring their levels in EphB2

Indexed as

HippocampusSignal TransductionAnimalsFearMiceNeuropilReceptor, EphB2RNAEphb2 protein, mouseReceptor, EphB2RNABasolateral amygdalaEphB2Fear conditioningGene expressionHippocampusLearning and memory

Identifiers

PMID36637747
OpenAlexW4315928320

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.