Evidence map›Paper›PMID 36637706›Full record

ArticleAnalytical sciences : the international journal of the Japan Society for Analytical Chemistry2023

Radioactive isotope separation with 3D-printed flow-based device.

Syohei Obata, Yumi Sugo, Hinako Manabe, Yuto Arima, Kei Toda, Noriko S Ishioka, Masanobu Mori, Shin-Ichi Ohira

Abstract read
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In one paragraph

Article in Analytical sciences : the international journal of the Japan Society for Analytical Chemistry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.5field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Syohei ObataDepartment of Chemistry, Kumamoto University, 2-39-1 Kurokami, Kumamoto, 860-8555, Japan.
Yumi SugoDepartment of Radiation-Applied Biology Research, Takasaki Advanced Radiation Research Institute, National Institutes for Quantum Science and Technology, 1233 Watanuki, Takasaki, 370-1292, Japan. sugo.yumi@qst.go.jp.
Hinako ManabeFaculty of Science and Technology, Kochi University, 2-5-1 Akebono-Cho, Kochi, 780-8520, Japan.
Yuto ArimaDepartment of Chemistry, Kumamoto University, 2-39-1 Kurokami, Kumamoto, 860-8555, Japan.
Kei TodaDepartment of Chemistry, Kumamoto University, 2-39-1 Kurokami, Kumamoto, 860-8555, Japan.
Noriko S IshiokaDepartment of Radiation-Applied Biology Research, Takasaki Advanced Radiation Research Institute, National Institutes for Quantum Science and Technology, 1233 Watanuki, Takasaki, 370-1292, Japan.
Masanobu MoriFaculty of Science and Technology, Kochi University, 2-5-1 Akebono-Cho, Kochi, 780-8520, Japan. mori@kochi-u.ac.jp.
Shin-Ichi OhiraDepartment of Chemistry, Kumamoto University, 2-39-1 Kurokami, Kumamoto, 860-8555, Japan. ohira@kumamoto-u.ac.jp.ORCID http://orcid.org/0000-0002-5958-339X
Kumamoto University · JPAkebono (Japan) · JPNational Institutes for Quantum Science and Technology · JP

Funding

Japan Society for the Promotion of Science London 20H03632Japan Society for the Promotion of Science London 21H02870
6 · The paper itself

Abstract

Radioactive isotope (RI) metals are a new type of tracer for positron emission tomography generated from the target metal by proton irradiation using a cyclotron. The generated metal RIs need to be separated from the target metal rapidly and effectively. In the present study, we developed a 3D-printed flow device to separate metal RIs from target metals. The separation was performed with selective formation of ethylenediaminetetraacetic acid (EDTA) complex based on the difference in formation constants. The RI metal selectively formed a EDTA complex, thus changing its ionic charge in solution. The solution was then introduced into a cation exchange column for selective adsorption of the target metal. The solution with added chelator and controlled pH was introduced into the developed system and automatically separated metal RI from target metals within 14 min. The separation method was applied to separate RI

Indexed as

3D-printed devicePositron emission tomographyRadioisotopesSeparation

Identifiers

PMID36637706
OpenAlexW4315928537

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.