Evidence map›Paper›PMID 36637659›Full record

ReviewOphthalmology and therapy2023

Fuchs Dystrophy and Cataract: Diagnosis, Evaluation and Treatment.

Muhammad Ali, Kyongjin Cho, Divya Srikumaran

Registry-linked trialOpen access · goldAbstract readReview
In one paragraph

Review in Ophthalmology and therapy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06966167 (Comparison of Outcomes Between Femtosecond Laser-Assisted and Conventional Phacoemulsification in Fuchs Endothelial Corneal Dystrophy Patients With Cataracts), which is not on this map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
6.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06966167 recruitingnot on this mapstarted 2025, after this paper: background citation

Comparison of Outcomes Between Femtosecond Laser-Assisted and Conventional Phacoemulsification in Fuchs Endothelial Corneal Dystrophy Patients With Cataracts

TypeobservationalSponsorEye & ENT Hospital of Fudan UniversityRan2025 to 2030Enrolled120ConditionsFuchs Endothelial Corneal Dystrophy, Cataract
3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
  2. Detection of subclinical corneal edema in fuchs' dystrophy using galilei tomography.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026
    Article
  3. Article
  4. Observational
  5. Review
  6. Article
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  9. Review
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  11. Review
  12. Review
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  20. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Muhammad AliVice Chair for Education, Wilmer Eye Institute, Johns Hopkins University, Baltimore, MD, USA.
Kyongjin ChoVice Chair for Education, Wilmer Eye Institute, Johns Hopkins University, Baltimore, MD, USA.
Divya SrikumaranVice Chair for Education, Wilmer Eye Institute, Johns Hopkins University, Baltimore, MD, USA. dsrikum1@jhmi.edu.ORCID http://orcid.org/0000-0003-2366-235X
Johns Hopkins University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Corneal endothelium plays an important role in maintaining hydration homeostasis and clarity of the cornea. Fuchs endothelial corneal dystrophy (FECD) affects the corneal endothelium resulting in edema and characteristic excrescences on the Descemet's membrane known as corneal guttae. Descemet membrane endothelial keratoplasty (DMEK) has evolved to become the standard of care for patients with FECD with excellent visual acuity outcomes. Patients with FECD may have coexisting cataracts and therefore may require a cataract surgery, which increases the risk of corneal decompensation. The presence of FECD may not only influence the choice of intraocular lens but vision outcomes can also be affected by the corneal condition. The ability to combine the surgeries further raises important considerations regarding the timing and sequence of DMEK and cataract extraction for patients with FECD. This review provides a guide for corneal surgeons in choosing between endothelial keratoplasty and cataract surgery-alone, in combination or sequential-in their management of patients with FECD.

Indexed as

Descemet membrane endothelial keratoplastyFuchs endothelial dystrophyTriple procedure

Identifiers

PMID36637659
PMCPMC10011243
OpenAlexW4315881005

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.