Evidence map›Paper›PMID 36637631›Full record

ReviewJournal of cancer survivorship : research and practice2023

Emerging and established therapies for chemotherapy-induced ototoxicity.

O'neil W Guthrie, Christopher Spankovich

Abstract readReview
PubMed Publisher
In one paragraph

Review in Journal of cancer survivorship : research and practice, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Treatment-related hearing loss in weekly versus triweekly cisplatin chemoradiation for head and neck cancer.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2024
    Article
  3. Article
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

O'neil W GuthrieCell & Molecular Pathology Laboratory, Communication Sciences and Disorders, Northern Arizona University, Flagstaff, AZ, USA.
Christopher SpankovichDepartment of Otolaryngology Head and Neck Surgery, University of Mississippi Medical Center, Jackson, MS, USA. cspankovich@umc.edu.
Northern Arizona University · USUniversity of Mississippi Medical Center · US

Funding

Ear Level Cooling for OtoprotectionR21DC020312 · NIDCD · UNIVERSITY OF MISSISSIPPI MED CTR · PI SPANKOVICH, CHRISTOPHER · 2022 to 2023
$426k
NIDCD NIH HHS R21DC20312
6 · The paper itself

Abstract

purposeOtotoxicity is considered a dose-limiting side effect of some chemotherapies. Hearing loss, in particular, can have significant implications for the quality of life for cancer survivors. Here, we review therapeutic approaches to mitigating ototoxicity related to chemotherapy.

methodsLiterature review.

conclusionsNumerous otoprotection strategies are undergoing active investigation. However, numerous challenges exist to confer adequate protection while retaining the anti-cancer efficacy of the chemotherapy. IMPLICATIONS FOR CANCER SURVIVORS: Ototoxicity can have significant implications for cancer survivors, notably those receiving cisplatin. Clinical translation of multiple otoprotection approaches will aid in limiting these consequences.

Indexed as

Antineoplastic AgentsCancer SurvivorsOtotoxicityCisplatinHumansQuality of LifeAntineoplastic AgentsCisplatinCisplatinHearing lossOtoprotectionOtotoxicity

Identifiers

PMID36637631
OpenAlexW4315928387

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.