Evidence map›Paper›PMID 36637500›Full record

ArticleLangenbeck's archives of surgery2023

Hepatic artery-related complications after live donor liver transplantation.

Viniyendra Pamecha, Piyush Kumar Sinha, Amar Mukund, Nilesh Sadashiv Patil, Nihar Mohapatra, Shalini Thapar, Ashok Choudhury, Gaurav Sindwani, Anubhav Harshit Kumar, Sahil Gupta

Erratum issuedAbstract read
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In one paragraph

Article in Langenbeck's archives of surgery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
2.5field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Viniyendra PamechaHepato-Pancreato-Biliary and Liver Transplant Surgery, Institute of Liver and Biliary Sciences, D-1, Vasant Kunj, New Delhi, 110070, India. viniyendra@yahoo.co.uk.ORCID http://orcid.org/0000-0002-2597-8625
Piyush Kumar SinhaHepato-Pancreato-Biliary and Liver Transplant Surgery, Institute of Liver and Biliary Sciences, D-1, Vasant Kunj, New Delhi, 110070, India.
Amar MukundInterventional Radiology, Institute of Liver and Biliary Sciences, New Delhi, India.
Nilesh Sadashiv PatilHepato-Pancreato-Biliary and Liver Transplant Surgery, Institute of Liver and Biliary Sciences, D-1, Vasant Kunj, New Delhi, 110070, India.
Nihar MohapatraHepato-Pancreato-Biliary and Liver Transplant Surgery, Institute of Liver and Biliary Sciences, D-1, Vasant Kunj, New Delhi, 110070, India.
Shalini ThaparRadiology, Institute of Liver and Biliary Sciences, New Delhi, India.
Ashok ChoudhuryHepatology, Institute of Liver and Biliary Sciences, New Delhi, India.
Gaurav SindwaniAnesthesiology, Institute of Liver and Biliary Sciences, New Delhi, India.
Anubhav Harshit KumarHepato-Pancreato-Biliary and Liver Transplant Surgery, Institute of Liver and Biliary Sciences, D-1, Vasant Kunj, New Delhi, 110070, India.
Sahil GuptaHepato-Pancreato-Biliary and Liver Transplant Surgery, Institute of Liver and Biliary Sciences, D-1, Vasant Kunj, New Delhi, 110070, India.
Institute of Liver and Biliary Sciences · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHepatic artery-related complications (HARC) after live donor liver transplantation (LDLT) is associated with high morbidity and mortality rate.

methodsProspectively maintained data from July 2011 to September 2020 was analyzed for etiology, detection, management, and outcome of HARC.

resultsSix hundred fifty-seven LDLT (adult 572/pediatrics 85) were performed during the study period. Twenty-one (3.2%) patient developed HARC; 16 (2.4%) hepatic artery thrombosis (HAT) and 5 (0.76%) non-thrombotic hepatic artery complication (NTHAC). Ninety percent (19/21) HARC were asymptomatic and detected on protocol Doppler. Median time to detection was day 4 (range - 1 to 35), which included 18 early (within 7 days) vs 3 late incidents. Only one pediatric patient had HAT. Seven patients underwent surgical revascularization, 11 had endovascular intervention and 3 with attenuated flow required only systemic anticoagulation. All NTHAC survived without any sequelae. Revascularization was successful in 81% (13/16) with HAT. Biliary complications were seen in 5 (23.8%); four were managed successfully. Overall mortality was 14.8% (3/21). The 1-year and 5-year survival were similar to those who did not develop HARC (80.9% vs 84.2%, p = 0.27 and 71.4% vs 75.19%, p = 0.36 respectively) but biliary complications were significantly higher (23.8% vs 14.2%, p = 0.03). On multivariate analysis, clockwise technique of arterial reconstruction was associated with decreased risk of HAT (1.7% vs 4.1% (p value - 0.003)).

conclusionTechnical refinement, early detection, and revascularization can achieve good outcome in patients with HARC after LDLT.

Indexed as

Liver DiseasesLiver TransplantationThrombosisAdultChildHepatic ArteryHumansLiving DonorsRetrospective StudiesTreatment OutcomeEndovascular interventionHepatic artery related complicationsLive donor liver transplantSurgical revascularization

Identifiers

PMID36637500
OpenAlexW4315866058

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.