Evidence map›Paper›PMID 36637410›Full record

ArticleEuropean heart journal. Quality of care & clinical outcomes2023

Machine learning for prediction of all-cause mortality after transcatheter aortic valve implantation.

Jacek Kwiecinski, Maciej Dabrowski, Luis Nombela-Franco, Kajetan Grodecki, Konrad Pieszko, Zbigniew Chmielak, Anna Pylko, Breda Hennessey, Lukasz Kalinczuk, Gabriela Tirado-Conte and 9 more

Abstract read
In one paragraph

Article in European heart journal. Quality of care & clinical outcomes, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 5 syntheses or guidelines pooled it.

  1. Pooled it
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  6. Article
  7. Superiority of the Rockwood Clinical Frailty Scale for Assessing Long-Term Outcome in Patients Undergoing Transcatheter Aortic Valve Implantation.Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2026
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  16. Advanced Cardiac Imaging in the Assessment of Aortic Stenosis.Journal of cardiovascular development and disease · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Jacek KwiecinskiDepartment of Interventional Cardiology and Angiology, Institute of Cardiology, Warsaw, Poland.
Maciej DabrowskiDepartment of Interventional Cardiology and Angiology, Institute of Cardiology, Warsaw, Poland.ORCID 0000-0002-7347-2514
Luis Nombela-FrancoCardiovascular Institute, Hospital Clinico San Carlos, IdISSC, Madrid, Spain.ORCID 0000-0003-3438-8907
Kajetan Grodecki1st Department of Cardiology, Medical University of Warsaw, Warsaw, Poland.
Konrad PieszkoDepartments of Medicine (Division of Artificial Intelligence in Medicine) and Biomedical Sciences, Cedars-Sinai Medical Center, 8700 Beverly Blvd, Metro 203, Los Angeles, CA 90048, USA.
Zbigniew ChmielakDepartment of Interventional Cardiology and Angiology, Institute of Cardiology, Warsaw, Poland.
Anna PylkoDepartment of Interventional Cardiology and Angiology, Institute of Cardiology, Warsaw, Poland.
Breda HennesseyCardiovascular Institute, Hospital Clinico San Carlos, IdISSC, Madrid, Spain.
Lukasz KalinczukDepartment of Interventional Cardiology and Angiology, Institute of Cardiology, Warsaw, Poland.ORCID 0000-0003-1657-8096
Gabriela Tirado-ConteCardiovascular Institute, Hospital Clinico San Carlos, IdISSC, Madrid, Spain.
Bartosz Rymuza1st Department of Cardiology, Medical University of Warsaw, Warsaw, Poland.
Janusz Kochman1st Department of Cardiology, Medical University of Warsaw, Warsaw, Poland.
Maksymilian P OpolskiDepartment of Interventional Cardiology and Angiology, Institute of Cardiology, Warsaw, Poland.
Zenon Huczek1st Department of Cardiology, Medical University of Warsaw, Warsaw, Poland.
Marc R DweckCentre for Cardiovascular Science, University of Edinburgh, Edinburgh, UK.
Damini DeyDepartments of Medicine (Division of Artificial Intelligence in Medicine) and Biomedical Sciences, Cedars-Sinai Medical Center, 8700 Beverly Blvd, Metro 203, Los Angeles, CA 90048, USA.ORCID 0000-0003-2236-6970
Pilar Jimenez-QuevedoCardiovascular Institute, Hospital Clinico San Carlos, IdISSC, Madrid, Spain.
Piotr SlomkaDepartments of Medicine (Division of Artificial Intelligence in Medicine) and Biomedical Sciences, Cedars-Sinai Medical Center, 8700 Beverly Blvd, Metro 203, Los Angeles, CA 90048, USA.ORCID 0000-0002-6110-938X
Adam WitkowskiDepartment of Interventional Cardiology and Angiology, Institute of Cardiology, Warsaw, Poland.ORCID 0000-0002-3514-2047

Funding

Integrated prediction of cardiovascular events by automated coronary plaque and pericoronary adipose tissue quantification from CT AngiographyR01HL148787 · NHLBI · CEDARS-SINAI MEDICAL CENTER · PI DEY, DAMINI · 2020 to 2023
$3.0M
Integrated analysis of coronary anatomy and biology with 18F-fluoride PET and CT angiographyR01HL135557 · NHLBI · CEDARS-SINAI MEDICAL CENTER · PI SLOMKA, PIOTR J · 2017 to 2020
$3.0M
Effect of Intensive Medical Treatment on Quantified Coronary Artery Plaque Components with Serial Coronary CTA in Women with Non-Obstructive CADR01HL151266 · NHLBI · CEDARS-SINAI MEDICAL CENTER · PI DEY, DAMINI, TAMARAPPOO, BALAJI K. · 2020 to 2023
$1.6M
British Heart Foundation FS/14/78/31020NHLBI NIH HHS R01 HL135557NHLBI NIH HHS R01HL135557NHLBI NIH HHS R01 HL148787NHLBI NIH HHS R01 HL151266NIH HHS
6 · The paper itself

Abstract

aimsPrediction of adverse events in mid-term follow-up after transcatheter aortic valve implantation (TAVI) is challenging. We sought to develop and validate a machine learning model for prediction of 1-year all-cause mortality in patients who underwent TAVI and were discharged following the index procedure. METHODS AND

resultsThe model was developed on data of patients who underwent TAVI at a high-volume centre between January 2013 and March 2019. Machine learning by extreme gradient boosting was trained and tested with repeated 10-fold hold-out testing using 34 pre- and 25 peri-procedural clinical variables. External validation was performed on unseen data from two other independent high-volume TAVI centres. Six hundred four patients (43% men, 81 ± 5 years old, EuroSCORE II 4.8 [3.0-6.3]%) in the derivation and 823 patients (46% men, 82 ± 5 years old, EuroSCORE II 4.7 [2.9-6.0]%) in the validation cohort underwent TAVI and were discharged home following the index procedure. Over the 12 months of follow-up, 68 (11%) and 95 (12%) subjects died in the derivation and validation cohorts, respectively. In external validation, the machine learning model had an area under the receiver-operator curve of 0.82 (0.78-0.87) for prediction of 1-year all-cause mortality following hospital discharge after TAVI, which was superior to pre- and peri-procedural clinical variables including age 0.52 (0.46-0.59) and the EuroSCORE II 0.57 (0.51-0.64), P < 0.001 for a difference.

conclusionMachine learning based on readily available clinical data allows accurate prediction of 1-year all-cause mortality following a successful TAVI.

Indexed as

Aortic Valve StenosisTranscatheter Aortic Valve ReplacementAgedAged, 80 and overAortic ValveFemaleHumansInfantMaleAortic stenosisArtificial intelligenceMachine learningTranscatheter aortic valve implantation

Identifiers

PMID36637410
PMCPMC10745254

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.