Evidence map›Paper›PMID 36637392›Full record

ArticleJournal of pediatric endocrinology & metabolism : JPEM2023

Relationships among biochemical measures in children with diabetic ketoacidosis.

Nicole S Glaser, Michael J Stoner, Maria Y Kwok, Kimberly S Quayle, Kathleen M Brown, Jeff E Schunk, Jennifer L Trainor, Julie K McManemy, Leah Tzimenatos, Arleta Rewers and 6 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of pediatric endocrinology & metabolism : JPEM, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 12 institutions in 1 country.

Nicole S GlaserDepartment of Pediatrics, University of California, Davis Health, University of California Davis, School of Medicine, Sacramento, USA.
Michael J StonerDivision of Emergency Medicine, Department of Pediatrics, Nationwide Children's Hospital, The Ohio State University School of Medicine, Columbus, USA.
Maria Y KwokDivision of Emergency Medicine, Department of Pediatrics, New York Presbyterian Morgan Stanley Children's Hospital, Columbia University College of Physicians and Surgeons, New York, USA.
Kimberly S QuayleDivision of Emergency Medicine, Department of Pediatrics, St. Louis Children's Hospital, Washington University School of Medicine in St. Louis, Saint Louis, USA.
Kathleen M BrownDivision of Emergency Medicine, Department of Pediatrics, Children's National Medical Center, The George Washington School of Medicine and Health Sciences, Washington DC, USA.
Jeff E SchunkDepartment of Pediatrics, University of Utah School of Medicine, Salt Lake City, USA.
Jennifer L TrainorDivision of Emergency Medicine, Department of Pediatrics, Ann and Robert H. Lurie Children's Hospital of Chicago, Northwestern University Feinberg School of Medicine, Chicago, USA.
Julie K McManemyDivision of Emergency Medicine, Department of Pediatrics, Texas Children's Hospital, Baylor College of Medicine, Houston, USA.
Leah TzimenatosDepartment of Emergency Medicine, University of California Davis Health, University of California Davis, School of Medicine, Sacramento, USA.
Arleta RewersDivision of Emergency Medicine, Department of Pediatrics, The Colorado Children's Hospital, University of Colorado-Denver School of Medicine, Denver, USA.
Lise E NigrovicDivision of Emergency Medicine, Department of Pediatrics, Boston Children's Hospital, Harvard Medical School, Boston, USA.
Jonathan E BennettDivision of Emergency Medicine, Nemours/A.I. DuPont Hospital for Children, Sidney Kimmel Medical College at Thomas Jefferson University, Philadelphia, USA.
Sage R MyersDivision of Emergency Medicine, Department of Pediatrics, Children's Hospital of Philadelphia, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, USA.
McKenna SmithDepartment of Pediatrics, University of Utah School of Medicine, Salt Lake City, USA.
T Charles CasperDepartment of Pediatrics, University of Utah School of Medicine, Salt Lake City, USA.
Nathan KuppermannDepartment of Pediatrics, University of California, Davis Health, University of California Davis, School of Medicine, Sacramento, USA.
University of California, Davis · USUniversity of Utah · USAlfred I. duPont Hospital for Children · USBoston Children's Hospital · USChildren's Hospital of Philadelphia · USChildren's National · USColumbia University · USLurie Children's Hospital · USSt. Louis Children's Hospital · USTexas Children's Hospital · USThe Ohio State University · USUniversity of Colorado Denver · US

Funding

Fluid Therapy and Cerebral Injury in Pediatric Diabetic KetoacidosisU01HD062417 · NICHD · UNIVERSITY OF CALIFORNIA AT DAVIS · PI GLASER, NICOLE S, KUPPERMANN, NATHAN · 2012 to 2014
$1.7M
NICHD NIH HHS U01 HD062417
6 · The paper itself

Abstract

objectivesInvestigating empirical relationships among laboratory measures in children with diabetic ketoacidosis (DKA) can provide insights into physiological alterations occurring during DKA. We determined whether alterations in laboratory measures during DKA conform to theoretical predictions.

methodsWe used Pearson correlation statistics and linear regression to investigate correlations between blood glucose, electrolytes, pH and PCO

resultspH and bicarbonate levels were strongly correlated (r=0.64), however, pH and PCO

conclusionsElevated glucose levels at DKA presentation largely reflect alterations in glomerular filtration rate. pH and PCO

Indexed as

Diabetes MellitusDiabetic KetoacidosisBlood GlucoseChildGlomerular Filtration RateGlucoseHumansBlood GlucoseGlucoseacid-base balancediabetesdiabetic ketoacidosiselectrolytes

Identifiers

PMID36637392
PMCPMC9986464
OpenAlexW4315927791

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.