Evidence map›Paper›PMID 36636806›Full record

ReviewMicrobial biotechnology2023

Derivation of the multiply-branched ergot alkaloid pathway of fungi.

Daniel G Panaccione

Open access · goldAbstract readReview
In one paragraph

Review in Microbial biotechnology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
13.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. The regulatory network ofMicrobiology spectrum · 2025
    Article
  5. Article
  6. Article
  7. A gene regulating ergot alkaloid biosynthesis inApplied and environmental microbiology · 2024
    Article
  8. Article
  9. Review
  10. Article
  11. Ergot Alkaloids Contribute to the Pathogenic Potential of the FungusApplied and environmental microbiology · 2023
    Article
  12. Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Daniel G PanaccioneDivision of Plant and Soil Sciences, West Virginia University, Morgantown, West Virginia, USA.ORCID 0000-0002-4159-164X
West Virginia University · US

Funding

Strategic Reprogramming of the Ergot Alkaloid PathwayR15GM114774 · NIGMS · WEST VIRGINIA UNIVERSITY · PI PANACCIONE, DANIEL G. · 2015 to 2023
$1.3M
NIGMS NIH HHS R15 GM114774
6 · The paper itself

Abstract

Ergot alkaloids are a large family of fungal specialized metabolites that are important as toxins in agriculture and as the foundation of powerful pharmaceuticals. Fungi from several lineages and diverse ecological niches produce ergot alkaloids from at least one of several branches of the ergot alkaloid pathway. The biochemical and genetic bases for the different branches have been established and are summarized briefly herein. Several pathway branches overlap among fungal lineages and ecological niches, indicating activities of ergot alkaloids benefit fungi in different environments and conditions. Understanding the functions of the multiple genes in each branch of the pathway allows researchers to parse the abundant genomic sequence data available in public databases in order to assess the ergot alkaloid biosynthesis capacity of previously unexplored fungi. Moreover, the characterization of the genes involved in the various branches provides opportunities and resources for the biotechnological manipulation of ergot alkaloids for experimentation and pharmaceutical development.

Indexed as

Ergot AlkaloidsFungiErgot Alkaloids

Identifiers

PMID36636806
PMCPMC10034635
OpenAlexW4315928617

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.