Evidence map›Paper›PMID 36636493›Full record

ArticleJournal of the Korean Academy of Child and Adolescent Psychiatry2023

A Validation Study of the CARS-2 Compared With the ADOS-2 in the Diagnosis of Autism Spectrum Disorder: A Suggestion for Cutoff Scores.

Seong-In Ji, Hyungseo Park, Sun Ah Yoon, Soon-Beom Hong

Open access · hybridAbstract read
In one paragraph

Article in Journal of the Korean Academy of Child and Adolescent Psychiatry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 24 citations in OpenAlex.

  1. Double-blind, sham-controlled, pilot study of trigeminal nerve stimulation for autism spectrum disorder.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2026
    Trial
  2. Trial
  3. Article
  4. Review
  5. Psychometric Properties of an Arabic Modified Childhood Autism Rating Scale 2 Standard Form.International journal of methods in psychiatric research · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. The Childhood Autism Rating Scale Second Edition (CARS2) and Its Applicability in an Iranian Sample.Autism research : official journal of the International Society for Autism Research · 2025
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Seong-In JiDepartment of Psychiatry, Seoul National University Hospital, Seoul, Korea.ORCID 0000-0002-1704-9703
Hyungseo ParkDepartment of Psychiatry, Seoul National University Hospital, Seoul, Korea.ORCID 0000-0002-1804-5595
Sun Ah YoonDepartment of Psychiatry, Seoul National University Hospital, Seoul, Korea.ORCID 0000-0001-7319-8992
Soon-Beom HongDivision of Child and Adolescent Psychiatry, Department of Psychiatry, Seoul National University College of Medicine, Seoul, Korea.ORCID 0000-0003-1030-0763
Seoul National University Hospital · KRSeoul National University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: This study examined the validity of the Childhood Autism Rating Scale, Second Edition (CARS-2) compared with the Autism Diagnostic Observation Schedule, Second Edition (ADOS-2) in identifying autism spectrum disorder (ASD). Methods: A total of 237 children were tested using both the CARS-2 and ADOS-2. We examined the correlation using Pearson's correlation analysis. In addition, we used a receiver operating characteristic graph to determine the optimal standard version of the CARS-2 (CARS2-ST) cutoff score for ASD diagnosis using the ADOS-2. Results: The concurrent validity of the CARS2-ST was demonstrated by a significant correlation with the ADOS-2 (r=0.864, p<0.001). The optimal CARS2-ST cutoff scores were 30 and 28.5 for identifying autism and autism spectrum, respectively, based on the ADOS-2. Conclusion: We suggest a newly derived CARS2-ST cutoff score of 28.5 for screening ASD and providing early intervention.

Indexed as

ADOS-2Autism spectrum disorderCARS-2DiagnosisScreening

Identifiers

PMID36636493
PMCPMC9816003
OpenAlexW4313579280

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.