Evidence map›Paper›PMID 36636436›Full record

ReviewJACC. CardioOncology2022

The Role of Single-Cell Profiling and Deep Immunophenotyping in Understanding Immune Therapy Cardiotoxicity.

Yuhsin Vivian Huang, Sarah Waliany, Daniel Lee, Francisco X Galdos, Ronald M Witteles, Joel W Neal, Alice C Fan, Holden T Maecker, Patricia K Nguyen, Sean M Wu and 1 more

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in JACC. CardioOncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Yuhsin Vivian HuangStanford Cardiovascular Institute, Stanford University, Stanford, California, USA.
Sarah WalianyDepartment of Medicine, Stanford University School of Medicine, Stanford, California, USA.
Daniel LeeStanford Cardiovascular Institute, Stanford University, Stanford, California, USA.
Francisco X GaldosStanford Cardiovascular Institute, Stanford University, Stanford, California, USA.
Ronald M WittelesStanford Cardiovascular Institute, Stanford University, Stanford, California, USA.
Joel W NealDepartment of Medicine, Stanford University School of Medicine, Stanford, California, USA.
Alice C FanDepartment of Medicine, Stanford University School of Medicine, Stanford, California, USA.
Holden T MaeckerDepartment of Microbiology and Immunology, Stanford University School of Medicine, Stanford, California, USA.
Patricia K NguyenStanford Cardiovascular Institute, Stanford University, Stanford, California, USA.
Sean M WuStanford Cardiovascular Institute, Stanford University, Stanford, California, USA.
Han ZhuStanford Cardiovascular Institute, Stanford University, Stanford, California, USA.

Funding

Identification of Causal T-Cell Mechanisms in Immune Checkpoint Inhibitor Induced MyocarditisK08HL161405 · NHLBI · STANFORD UNIVERSITY · PI Han Zhu · 2022 to 2026
$880k
NHLBI NIH HHS K08 HL161405
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

CITE-seq, cellular indexing of transcriptomes and epitopes by sequencingCTLA-4, cytotoxic T-lymphocyte antigen 4CyTOF, time-of-flight mass cytometryICI, immune checkpoint inhibitorimmunotherapyIRAE, immune-related adverse eventmass cytometrymonoclonal antibodymyocarditisPD-1, programmed death-1scRNA-seq, single-cell RNA sequencingscTCR-seq, single-cell T-cell receptor sequencingtreatment

Identifiers

PMID36636436
PMCPMC9830194

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.