Evidence map›Paper›PMID 36636260›Full record

SynthesisJournal of interventional cardiology2022

Drug-Coated Balloons for Acute Myocardial Infarction: A Metaanalysis of Randomized Clinical Trials.

Yuxuan Zhang, Delong Chen, Qichao Dong, Yi Xu, Jiacheng Fang, Huaqing Zhang, Jun Jiang

Abstract readMeta-AnalysisReview
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Journal of interventional cardiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yuxuan ZhangDepartment of Cardiology, Second Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China.ORCID https://orcid.org/0000-0001-9407-9589
Delong ChenDepartment of Cardiology, Second Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China.ORCID https://orcid.org/0000-0002-7313-2990
Qichao DongDepartment of Cardiology, Second Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China.ORCID https://orcid.org/0000-0001-9169-552X
Yi XuDepartment of Cardiology, Ningbo First Hospital, Ningbo, China.ORCID https://orcid.org/0000-0002-3814-0506
Jiacheng FangDepartment of Cardiology, Second Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China.ORCID https://orcid.org/0000-0002-7038-9897
Huaqing ZhangDepartment of Clinical Engineering, Second Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China.ORCID https://orcid.org/0000-0001-7381-3238
Jun JiangDepartment of Cardiology, Second Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China.ORCID https://orcid.org/0000-0001-6926-9516

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The role of a drug-coated balloon (DCB) in the treatment of acute myocardial infarction (AMI) is not well established. Methods: Five databases were searched for randomized controlled trials that compared DCB with stents in the treatment of AMI from their inception to 30 July 2021. The primary clinical endpoint was major adverse cardiac events (MACEs). Summary estimations were conducted using fixed-effects analysis complemented by several subgroups. The protocol was registered with PROSPERO (https://clinicaltrials.gov/ct2/show/CRD42021272886). Results: A total of 4 randomized controlled trials with 485 patients were included. On routine clinical follow-up, DCB was associated with no difference in the incidence of MACEs compared with control (risk ratio [RR] 0.59 [0.31 to 1.13]; Conclusions: In treatment of patients with AMI, DCB might be a feasible interventional strategy versus control as it associated with comparable clinical outcomes. Future large-volume, well-designed randomized controlled trials to evaluating the role of the DCB in this setting are warranted.

Indexed as

Angioplasty, Balloon, CoronaryCoronary RestenosisDrug-Eluting StentsMyocardial InfarctionCoated Materials, BiocompatibleHumansRandomized Controlled Trials as TopicTreatment OutcomeCoated Materials, Biocompatible

Identifiers

PMID36636260
PMCPMC9810407

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.