Evidence map›Paper›PMID 36635627›Full record

Trial reportBMC anesthesiology2023

Addition of preoperative transversus abdominis plane block to multimodal analgesia in open gynecological surgery: a randomized controlled trial.

Zhi Yu Geng, Yan Zhang, Hui Bi, Dai Zhang, Zheng Li, Lu Jiang, Lin Lin Song, Xue Ying Li

Registry-linked trialOpen access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in BMC anesthesiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06847022 (Efficacy of Ultrasound-guided Transversalis Fascia Plane Block), which is not on this map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
3.5field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06847022 nacompletednot on this mapstarted 2024, after this paper: background citation

Efficacy of Ultrasound-guided Transversalis Fascia Plane Block (TFPB) in Controlling Postoperative Pain After Transverse Incision in Gynecologic Surgery

TypeinterventionalSponsorThammasat UniversityRan2024 to 2025Enrolled32ConditionsTransversalis Fascia Plane Block, Gynecologic Surgical ProceduresArmsUS-guided transversalis fascia plane block
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Zhi Yu GengDepartment of Anesthesiology, Peking University First Hospital, Beijing, China. gengzhiyu2013@163.com.
Yan ZhangDepartment of Obstetrics and Gynecology, Peking University First Hospital, Beijing, China.
Hui BiDepartment of Obstetrics and Gynecology, Peking University First Hospital, Beijing, China.
Dai ZhangDepartment of Obstetrics and Gynecology, Peking University First Hospital, Beijing, China.
Zheng LiDepartment of Obstetrics and Gynecology, Peking University First Hospital, Beijing, China.
Lu JiangDepartment of Obstetrics and Gynecology, Peking University First Hospital, Beijing, China.
Lin Lin SongDepartment of Anesthesiology, Peking University First Hospital, Beijing, China.
Xue Ying LiDepartment of Biostatics, Peking University First Hospital, Beijing, China.
Peking University · CNPeking University First Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTransversus abdominis plane (TAP) block can provide effective analgesia for abdominal surgery. However, it was questionable whether TAP had additional effect in the context of multimodal analgesia (MMA). Therefore, this study aimed to assess the additional analgesic effect of preoperative TAP block when added to MMA protocol in open gynecological surgery.

methodsIn this prospective, randomized-controlled trial, 64 patients scheduled for open gynecological surgery were randomized to receive preoperative TAP block (Study group, n = 32) or placebo (Control group, n = 32) in addition to MMA protocol comprising dexamethasone, acetaminophen, flurbiprofen and celecoxib, and rescued morphine analgesia. The primary outcome was rescued morphine within 24 h after surgery. Secondary outcomes included pain scores, adverse effects, quality of recovery measured by 40-item quality of recovery questionnaire score (QoR-40) at 24 h, and quality of life measured with short-form health survey (SF - 36) on postoperative day (POD) 30.

resultsThe Study group had less rescued morphine than the control group within 24 h [5 (2-9) vs. 8.5 (5-12.8) mg, P = 0.013]. The Study group had lower pain scores at 1 h [3 (2-4) vs. 4 (3-5), P = 0.007], 2 h [3 (2-4) vs. 3.5 (3-5), P = 0.010] and 6 h [3 (2-3) vs. 3 (2.3-4), P = 0.028], lower incidence of nausea at 48 h (25.8% vs. 50%, P = 0.039), and higher satisfaction score [10 (10-10) vs. 10 (8-10), P = 0.041]. The SF-36 bodily pain score on POD 30 was higher in the Study group (59 ± 13 vs. 49 ± 16, P = 0.023).

conclusionsPreoperative TAP block had additional analgesic effect for open gynecological surgery when used as part of multimodal analgesia. Rescued morphine within 24 h was significantly reduced and the SF-36 bodily pain dimension at 30 days after surgery was significantly improved.

trial registrationwww.chictr.org.cn (ChiCTR2000040343, on Nov 28 2020).

Indexed as

AnalgesiaAnalgesics, OpioidAbdominal MusclesAnesthetics, LocalDouble-Blind MethodFemaleGynecologic Surgical ProceduresHumansMorphinePostoperative PainProspective StudiesQuality of LifeAnalgesics, OpioidAnesthetics, LocalMorphineGynecologicMultimodal analgesiaPostoperative analgesiaRecovery Transversus abdominis plane block

Identifiers

PMID36635627
PMCPMC9835300
OpenAlexW4315651798

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.