ReviewApplied microbiology and biotechnology2023
Synthesis, biomedical applications, and toxicity of CuO nanoparticles.
Review in Applied microbiology and biotechnology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
55 citing papers in PubMed, 232 citations in OpenAlex.
- Anti-inflammatory role of metal and metal oxide nanoparticles: a review of toxicity, green synthesis, and immunomodulatory mechanisms.Inflammopharmacology · 2026Review
- Antimicrobial Properties of Ti- and Zr-Based Nanotextured Thin Film Metallic Glasses AgainstBiomolecules · 2026Article
- Plant Bioactive Compounds at the Interface of Extraction Science, Green Nanoparticles and Applied Biotechnology: A Narrative Review.Molecules (Basel, Switzerland) · 2026Review
- Microbial Synthesis of Nano Trace Minerals: A Comprehensive Review on Synthesis, Characterization, Biological Effects and Applications in Farm Animals.Biological trace element research · 2026Review
- A quenched electrochemiluminescence immunosensor based on luminol-Au NPs/Co-Fe-MOF and CuO@UiO-66-NHMikrochimica acta · 2026Article
- Synthesis of Crystalline Copper Oxide (CuO) Nanoparticles via a Combined Polyol and Thermal Decomposition in Air.Materials (Basel, Switzerland) · 2026Article
- A Cost-Effective Approach to Triphenylamine-Assisted Fabrication of Stable CuNanotechnology, science and applications · 2026Article
- Kidneys Toxicity and Biodistribution of Albumin-Based Gold and Silver Nanoclusters.Current drug delivery · 2026Article
- A Comprehensive Review on Copper Oxide Nanoparticles: Physicochemical Parameters, Pharmacological Potential and Pathophysiological Effects.International journal of nanomedicine · 2026Review
- Plantain peel extract-mediated synthesis of CuO nanoparticles: comprehensive characterization, bioinertnessADMET & DMPK · 2026Article
- Toxicodynamics and Human Health Risks of Metal Nanoparticles: A Review of AI/ML-Based Predictive Nanotoxicology.International journal of nanomedicine · 2026Review
- Structure, Ecotoxicity, Redox and Bactericidal Activity of Cu-Containing Nanocrystalline Ferrites.Molecules (Basel, Switzerland) · 2025Article
- Antimicrobial activity of gentamicin-conjugated monometallic and bimetallic nanoparticles against multidrug-resistant Klebsiella pneumoniae strains.Folia microbiologica · 2025Article
- Combined DFT and experimental study of CuO and Ni-CuO nanoparticles: structural characterization, photocatalytic degradation, and antimicrobial activities.RSC advances · 2025Article
- In vitro release kinetics of bioactive compounds (gallic acid, ellagic acid, and eugenol) from chitosan polymer and the bioactivity of herb-loaded chitosan-CuO nanocomposites.Scientific reports · 2025Article
- Engineered anti-cancer nanomedicine for synergistic cuproptosis-immunotherapy.Materials today. Bio · 2025Review
- Advances in Antimicrobial Applications of Ag, Cu, and AgCu Nanoparticle-Doped Polymeric Composite Materials: A Comprehensive Review.ACS nano · 2025Review
- Green nanoscience for healthcare: Advancing biomedical innovation through eco-synthesized nanoparticle.Biotechnology reports (Amsterdam, Netherlands) · 2025Review
- Green synthesis of copper hydroxide nanorods using3 Biotech · 2025Article
- Biocontrol and Nanotechnology Strategies for Postharvest Disease Management in Fruits and Vegetables: A Comprehensive Review.Foods (Basel, Switzerland) · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Versatile nature of copper oxide nanoparticles (CuO NPs) has made them an imperative nanomaterial being employed in nanomedicine. Various physical, chemical, and biological methodologies are in use for the preparation of CuO NPs. The physicochemical and biological properties of CuO NPs are primarily affected by their method of fabrication; therefore, selectivity of a synthetic technique is immensely important that makes these NPs appropriate for a specific biomedical application. The deliberate use of CuO NPs in biomedicine questions their biocompatible nature. For this reason, the present review has been designed to focus on the approaches employed for the synthesis of CuO NPs; their biomedical applications highlighting antimicrobial, anticancer, and antioxidant studies; and most importantly, the in vitro and in vivo toxicity associated with these NPs. This comprehensive overview of CuO NPs is unique and novel as it emphasizes on biomedical applications of CuO NPs along with its toxicological assessments which would be useful in providing core knowledge to researchers working in these domains for planning and conducting futuristic studies. KEY POINTS: • The recent methods for fabrication of CuO nanoparticles have been discussed with emphasis on green synthesis methods for different biomedical approaches. • Antibacterial, antioxidant, anticancer, antiparasitic, antidiabetic, and antiviral properties of CuO nanoparticles have been explained. • In vitro and in vivo toxicological studies of CuO nanoparticles exploited along with their respective mechanisms.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.