Evidence map›Paper›PMID 36635373›Full record

ArticleIntensive care medicine experimental2023

A deep learning model for the classification of atrial fibrillation in critically ill patients.

Brian Chen, David M Maslove, Jeffrey D Curran, Alexander Hamilton, Philip R Laird, Parvin Mousavi, Stephanie Sibley

Abstract read
In one paragraph

Article in Intensive care medicine experimental, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Brian ChenSchool of Computing, Queen's University, Kingston, Canada.
David M MasloveDepartment of Critical Care Medicine, Queen's University, 76 Stuart Street, Kingston, ON, K7L 2V7, Canada.
Jeffrey D CurranDepartment of Critical Care Medicine, Queen's University, 76 Stuart Street, Kingston, ON, K7L 2V7, Canada.
Alexander HamiltonCentre for Health Innovation, Queen's University, Kingston, Canada.
Philip R LairdDepartment of Critical Care Medicine, Queen's University, 76 Stuart Street, Kingston, ON, K7L 2V7, Canada.
Parvin MousaviSchool of Computing, Queen's University, Kingston, Canada.
Stephanie SibleyDepartment of Critical Care Medicine, Queen's University, 76 Stuart Street, Kingston, ON, K7L 2V7, Canada. stephanie.sibley@kingstonhsc.ca.ORCID http://orcid.org/0000-0003-2229-9747

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAtrial fibrillation (AF) is the most common cardiac arrhythmia in the intensive care unit and is associated with increased morbidity and mortality. New-onset atrial fibrillation (NOAF) is often initially paroxysmal and fleeting, making it difficult to diagnose, and therefore difficult to understand the true burden of disease. Automated algorithms to detect AF in the ICU have been advocated as a means to better quantify its true burden.

resultsWe used a publicly available 12-lead ECG dataset to train a deep learning model for the classification of AF. We then conducted an external independent validation of the model using continuous telemetry data from 984 critically ill patients collected in our institutional database. Performance metrics were stratified by signal quality, classified as either clean or noisy. The deep learning model was able to classify AF with an overall sensitivity of 84%, specificity of 89%, positive predictive value (PPV) of 55%, and negative predictive value of 97%. Performance was improved in clean data as compared to noisy data, most notably with respect to PPV and specificity.

conclusionsThis model demonstrates that computational detection of AF is currently feasible and effective. This approach stands to improve the efficiency of retrospective and prospective research into AF in the ICU by automating AF detection, and enabling precise quantification of overall AF burden.

Indexed as

Atrial fibrillationCritical careDeep learning

Identifiers

PMID36635373
PMCPMC9837355

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.