ArticleScientific reports2023
Reduced bone formation and increased bone resorption drive bone loss in Eimeria infected broilers.
Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 37 citations in OpenAlex.
- Dietary Artemisia annua leaf powder modulates intestinal response and cecal microbiota of broiler chickens during peak Eimeria infection.Poultry science · 2026Article
- Dietary Brown Mushroom Stem Powder Modulates Ileal Morphology and Barrier-Related Gene Expression in Layer Chicks.Animals : an open access journal from MDPI · 2026Article
- Effect of dietary wheat on the progression of Histomonas meleagridis infection in turkey poults.Poultry science · 2026Article
- Interactive effects of the feed-borne mycotoxin deoxynivalenol and a mixed-species Eimeria challenge on layer pullets during the transition to lay.Poultry science · 2026Article
- Wheat levels have minor effects on the progression of coccidiosis in turkey poults.Poultry science · 2026Article
- Exploring the interplay betweenThe veterinary quarterly · 2025Review
- The influence of parasitic infection (Eimeria spp.) on bone and cartilage tissue in an animal model.Scientific reports · 2025Article
- Potential effect ofFrontiers in cellular and infection microbiology · 2025Article
- Large-Scale Field Trials of anVaccines · 2024Article
- Coccidiosis in Egg-Laying Hens and Potential Nutritional Strategies to Modulate Performance, Gut Health, and Immune Response.Animals : an open access journal from MDPI · 2024Review
- Effects of Methionine Supplementation Levels in Normal or Reduced Protein Diets on the Body Composition and Femur Bone Characteristics of Broilers Challenged with Coccidia.Animals : an open access journal from MDPI · 2024Article
- Article
- Dietary Spirulina effects in Eimeria-challenged broiler chickens: growth performance, nutrient digestibility, intestinal morphology, serum biomarkers, and gene expression.Journal of animal science · 2024Article
- Effects ofFrontiers in physiology · 2024Article
- Applications of Enteroendocrine Cells (EECs) Hormone: Applicability on Feed Intake and Nutrient Absorption in Chickens.Animals : an open access journal from MDPI · 2023Review
- The Functional Roles of Methionine and Arginine in Intestinal and Bone Health of Poultry: Review.Animals : an open access journal from MDPI · 2023Review
- Effects of DifferentAnimals : an open access journal from MDPI · 2023Article
- Evaluation of a dacitic (rhyolitic) tuff breccia use on performance, inflammatory, and antioxidant responses in broilers mildly challenged with Eimeria spp.Poultry science · 2023Article
- Osteoimmunology: A Link between Gastrointestinal Diseases and Skeletal Health in Chickens.Animals : an open access journal from MDPI · 2023Review
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Coccidiosis is an economically significant disease in the global poultry industry, but little is known about the mechanisms of bone defects caused by coccidiosis; thus, the study focused on effects of coccidiosis on the bone homeostasis of young broiler chickens. A total of 480 male Cobb500 broilers were randomly allocated into four treatment groups, including an uninfected control consuming diet ad libitum, two infected groups were orally gavaged with two different concentrations of sporulated Eimeria oocysts, and an uninfected pair-fed group fed the same amount of feed as the high Eimeria-infected group consumed. Growth performance and feed intake were recorded, and samples were collected on 6 days post infection. Results indicated that coccidiosis increased systemic oxidative status and elevated immune response in bone marrow, suppressing bone growth rate (P < 0.05) and increasing bone resorption (P < 0.05) which led to lower bone mineral density (P < 0.05) and mineral content (P < 0.05) under Eimeria infection. With the same amount of feed intake, the uninfected pair-fed group showed a distinguished bone formation rate and bone resorption level compared with the Eimeria infected groups. In conclusion, inflammatory immune response and oxidative stress in broilers after Eimeria infection were closely associated with altered bone homeostasis, highlighting the role of inflammation and oxidative stress in broiler bone homeostasis during coccidiosis.
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