Evidence map›Paper›PMID 36635037›Full record

ArticleBMJ open2023

Associations between HIV status and self-reported hypertension in a high HIV prevalence sub-Saharan African population: a cross-sectional study.

Katherine Davis, Louisa Moorhouse, Rufurwokuda Maswera, Phyllis Mandizvidza, Tawanda Dadirai, Tafadzwa Museka, Constance Nyamukapa, Mikaela Smit, Simon Gregson

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMJ open, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
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  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Katherine DavisMRC Centre for Global Infectious Disease Analysis, Department of Infectious Disease Epidemiology, Imperial College London, London, UK K.davis18@imperial.ac.uk.ORCID 0000-0002-3291-649X
Louisa MoorhouseMRC Centre for Global Infectious Disease Analysis, Department of Infectious Disease Epidemiology, Imperial College London, London, UK.
Rufurwokuda MasweraBiomedical Research and Training Institute, Harare, Zimbabwe.
Phyllis MandizvidzaBiomedical Research and Training Institute, Harare, Zimbabwe.
Tawanda DadiraiBiomedical Research and Training Institute, Harare, Zimbabwe.
Tafadzwa MusekaBiomedical Research and Training Institute, Harare, Zimbabwe.
Constance NyamukapaMRC Centre for Global Infectious Disease Analysis, Department of Infectious Disease Epidemiology, Imperial College London, London, UK.
Mikaela SmitMRC Centre for Global Infectious Disease Analysis, Department of Infectious Disease Epidemiology, Imperial College London, London, UK.
Simon GregsonMRC Centre for Global Infectious Disease Analysis, Department of Infectious Disease Epidemiology, Imperial College London, London, UK.
Biomedical Research and Training Institute · ZWLondon Centre for Neglected Tropical Disease Research · GB

Funding

Medical Research Council MR/R015600/1PEPFARWellcome Trust 220098/Z/20/Z
6 · The paper itself

Abstract

objectivesThis study examined whether HIV status and antiretroviral therapy (ART) exposure were associated with self-reported hypertension in Zimbabwe.

designStudy data were taken from a cross-sectional, general population survey, which included HIV testing (July 2018-December 2019).

settingThe data were collected in Manicaland Province, Zimbabwe.

participants9780 people aged 15 years and above were included. OUTCOME MEASURE: Self-reported hypertension was the outcome measure. This was defined as reporting a previous diagnosis of hypertension by a doctor or nurse. After weighting of survey responses by age and sex using household census data, χ

resultsThe weighted prevalence of self-reported hypertension was 13.6% (95% CI 12.9% to 14.2%) and the weighted prevalence of HIV was 11.1% (10.4% to 11.7%). In univariable analyses, there was no evidence of a difference in the weighted prevalence of self-reported hypertension between people living with HIV (PLHIV) and HIV-negative people (14.1%, 11.9% to 16.3% vs 13.3%, 12.6% to 14.0%; p=0.503) or between ART-exposed and ART-naive PLHIV (14.8%, 12.0% to 17.7% vs 12.8%, 9.1% to 16.4%,p=0.388). Adjusting for socio-demographic variables in logistic regression did not alter this finding (ORs:HIV status:0.88, 0.70 to 1.10, p=0.261; ART exposure:0.83, 0.53 to 1.30, p=0.411).

conclusionsApproximately one in seven PLHIV self-reported having hypertension, highlighting an important burden of disease. However, no associations were found between HIV status or ART exposure and self-reported hypertension, suggesting that it will be valuable to focus on managing other risk factors for hypertension in this population. These findings should be fully accounted for as Zimbabwe reorients its health system towards non-communicable disease control and management.

Indexed as

HIV InfectionsHypertensionAnti-Retroviral AgentsCross-Sectional StudiesHIV TestingHumansPrevalenceSelf ReportZimbabweAnti-Retroviral AgentsepidemiologyHIV & AIDShypertensionpublic health

Identifiers

PMID36635037
PMCPMC9843216
OpenAlexW4315785106

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.