Evidence map›Paper›PMID 36634643›Full record

ArticleAudiology & neuro-otology2023

Ankle Audiometry: A Clinical Test for the Enhanced Hearing Sensitivity for Body Sounds in Superior Canal Dehiscence Syndrome.

Luca Verrecchia, Karl-Johan Fredén Jansson, Magnus Westin, Aleksandr Velikoselskii, Sabine Reinfeldt, Bo Håkansson

Registry-linked trialOpen access · hybridAbstract read
In one paragraph

Article in Audiology & neuro-otology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07384091 (The Diagnostic Accuracy of Ankle Audiometry Performed With the B250 for Superior Canal Dehiscence Syndrome in Patients Affected by Pulsatile Tinnitus and/or Autophony Disorders), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07384091 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

The Diagnostic Accuracy of Ankle Audiometry Performed With the B250 for Superior Canal Dehiscence Syndrome in Patients Affected by Pulsatile Tinnitus and/or Autophony Disorders

TypeinterventionalSponsorRegion StockholmRan2026 to 2026Enrolled30ConditionsSuperior Canal Dehiscence Syndrome, Autophony, Pulsatile TinnitusArmsAnkle audiometry performed with the B250 transducer
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Luca VerrecchiaAudiology and Neurotology Department, ENT, Karolinska University Hospital, Stockholm, Sweden.
Karl-Johan Fredén JanssonDepartment of Electrical Engineering, Chalmers University of Technology, Gothenburg, Sweden.
Magnus WestinAudiology and Neurotology Department, ENT, Karolinska University Hospital, Stockholm, Sweden.
Aleksandr VelikoselskiiAudiology and Neurotology Department, ENT, Karolinska University Hospital, Stockholm, Sweden.
Sabine ReinfeldtDepartment of Electrical Engineering, Chalmers University of Technology, Gothenburg, Sweden.
Bo HåkanssonDepartment of Electrical Engineering, Chalmers University of Technology, Gothenburg, Sweden.
Chalmers University of Technology · SEKarolinska University Hospital · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe aim of this study was to develop a clinical test for body sounds' hypersensitivity in superior canal dehiscence syndrome (SCDS).

methodCase-control study, 20 patients affected by SCDS and body sounds' hypersensitivity and 20 control matched subjects tested with a new test called ankle audiometry (AA). The AA consisted of a psychoacoustic hearing test in which the stimulus was substituted by a controlled bone vibration at 125, 250, 500, and 750 Hz, delivered at the medial malleolus by a steel spring-attached bone transducer prototype B250. For each subject, it was defined an index side (the other being non-index), the one with major symptoms in cases or best threshold for each tested frequency in controls. In 3 patients, the AA was measured before and after SCDS surgery.

resultsThe AA thresholds for index side were significantly lower in SCDS patients (115.6 ± 10.5 dB force level [FL]) than in control subjects (126.4 ± 8.56 dB FL). In particular, the largest difference was observed at 250 Hz (-16.5 dB). AA thresholds in patients were significantly lower at index side in comparison with non-index side (124.2 ± 11.4 dB FL). The response obtained with 250 Hz stimuli outperformed the other frequencies, in terms of diagnostic accuracy for SCDS. At specific thresholds' levels (120 dB FL), AA showed relevant sensitivity (90%) and specificity (80%) for SCDS. AA did not significantly correlate to other clinical markers of SCDS such as the bone and air conducted hearing thresholds and the vestibular evoked myogenic potentials. The AA thresholds were significantly modified by surgical intervention, passing from 119.2 ± 9.7 to 130.4 ± 9.4 dB FL in 3 patients, following their relief in body sounds' hypersensitivity.

conclusionAA showed interesting diagnostic features in SCDS with significantly lower hearing thresholds in SCDS patients when compared to healthy matched subjects. Moreover, AA could identify the affected or more affected side in SCDS patients, with a significant threshold elevation after SCDS surgery, corresponding in body sounds' hypersensitivity relief. Clinically, AA may represent a first objective measure of body sounds' hypersensitivity in SCDS and, accordingly, be an accessible screening test for SCDS in not tertiary audiological centers.

Indexed as

Semicircular Canal DehiscenceVestibular Evoked Myogenic PotentialsAnkleAudiometryCase-Control StudiesHearingHumansSemicircular CanalsAutophonyB250HyperacusisSuperior canal dehiscenceSuperior canal dehiscence syndrome

Identifiers

PMID36634643
PMCPMC10273915
OpenAlexW4315777826

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.