Evidence map›Paper›PMID 36634348›Full record

ArticleBiochemistry2023

Inside-Out Design of Zinc-Binding Proteins with Non-Native Backbones.

Sharon L Guffy, Surya V S R K Pulavarti, Joseph Harrison, Drew Fleming, Thomas Szyperski, Brian Kuhlman

Open access · greenAbstract read
In one paragraph

Article in Biochemistry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. De novo design of stable proteins that efficaciously inhibit oncogenic G proteins.Protein science : a publication of the Protein Society · 2023
    Article
  2. bioRxiv : the preprint server for biology · 2023
    Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Sharon L GuffyDepartment of Biochemistry and Biophysics, University of North Carolina, Chapel Hill, North Carolina 27599, United States.
Surya V S R K PulavartiDepartment of Chemistry, State University of New York, Buffalo, New York 14260, United States.
Joseph HarrisonDepartment of Biochemistry and Biophysics, University of North Carolina, Chapel Hill, North Carolina 27599, United States.
Drew FlemingDepartment of Biochemistry and Biophysics, University of North Carolina, Chapel Hill, North Carolina 27599, United States.
Thomas SzyperskiDepartment of Chemistry, State University of New York, Buffalo, New York 14260, United States.ORCID 0000-0003-0272-1373
Brian KuhlmanDepartment of Biochemistry and Biophysics, University of North Carolina, Chapel Hill, North Carolina 27599, United States.ORCID 0000-0003-4907-9699
University of North Carolina at Chapel Hill · USUniversity at Buffalo, State University of New York · US

Funding

GPU workstation for deep learning-based protein design and cryo-EM data processingR35GM131923 · NIGMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BRIAN A KUHLMAN · 2019 to 2026
$6.1M
MOLECULAR AND CELLULAR BIOPHYSICS TRAINING PROGRAMT32GM008570 · NIGMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI KUHLMAN, BRIAN A, SLEP, KEVIN C · 1995 to 2022
$5.1M
NIGMS NIH HHS R35 GM131923NIGMS NIH HHS T32 GM008570
6 · The paper itself

Abstract

The

Indexed as

ProteinsZincAmino Acid SequenceLigandsProtein ConformationRetrospective StudiesLigandsProteinsZinc

Identifiers

PMID36634348
PMCPMC9939277
OpenAlexW4315778277

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.