Evidence map›Paper›PMID 36634304›Full record

ArticleBlood2023

CREBBP alterations are associated with a poor prognosis in de novo AML.

Adam J Lamble, Kohei Hagiwara, Robert B Gerbing, Jenny L Smith, Pandurang Kolekar, Rhonda E Ries, Edward A Kolb, Todd A Alonzo, Xiaotu Ma, Soheil Meshinchi

Abstract read
In one paragraph

Article in Blood, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. A Pre-Leukemic DNA Methylation Signature in Healthy Individuals at Higher Risk for Developing Myeloid Malignancy.Clinical cancer research : an official journal of the American Association for Cancer Research · 2024
    Article
  8. Review
  9. Review
  10. Article
  11. Review
  12. Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Adam J LambleDivision of Hematology and Oncology, Seattle Children's Hospital, Seattle, WA.
Kohei HagiwaraDepartment of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN.
Robert B GerbingChildren's Oncology Group, Monrovia, CA.
Jenny L SmithClinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA.
Pandurang KolekarDepartment of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN.ORCID 0000-0003-0044-0076
Rhonda E RiesClinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA.
Edward A KolbDivision of Oncology, Nemours Alfred I. duPont Hospital for Children, Wilmington, DE.
Todd A AlonzoChildren's Oncology Group, Monrovia, CA.
Xiaotu MaDepartment of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN.
Soheil MeshinchiClinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA.

Funding

NCTN BIQSFP ANBL1531 (NRT)U10CA180886 · NCI · PUBLIC HEALTH INSTITUTE · PI Douglas S. Hawkins · 2014 to 2026
$390.6M
COG SDMC - Statistics CoreU10CA180899 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI TODD A ALONZO · 2014 to 2026
$132.8M
NCI NIH HHS U10 CA180886NCI NIH HHS U10 CA180899
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Leukemia, Myeloid, AcuteCREB-Binding ProteinHumansMutationPrognosisCREB-Binding ProteinCREBBP protein, human

Identifiers

PMID36634304
PMCPMC10273087

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.