Evidence map›Paper›PMID 36634299›Full record

ArticleJCO precision oncology2023

Cancer Risk Associated With

Shelly Cummings, Andrew Alfonso, Elisha Hughes, Matt Kucera, Brent Mabey, Nanda Singh, Charis Eng

Open access · hybridAbstract read
In one paragraph

Article in JCO precision oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Double jeopardy: howFrontiers in cell and developmental biology · 2026
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  7. Cowden Syndrome and Oral Lesions: A Case Report Using MLPA.The American journal of case reports · 2025
    Article
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  10. Establishment of Novel High-Grade Serous Ovarian Carcinoma Cell Line OVAR79.International journal of molecular sciences · 2024
    Article
  11. Review
  12. Review
  13. Review
  14. Article
  15. Review
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Shelly CummingsMyriad Genetics Inc, Salt Lake City, UT.ORCID 0000-0001-6901-9664
Andrew AlfonsoMyriad Genetics Inc, Salt Lake City, UT.ORCID 0000-0001-6421-9720
Elisha HughesMyriad Genetics Inc, Salt Lake City, UT.ORCID 0000-0002-3145-3913
Matt KuceraMyriad Genetics Inc, Salt Lake City, UT.
Brent MabeyMyriad Genetics Inc, Salt Lake City, UT.
Nanda SinghMyriad Genetics Inc, Salt Lake City, UT.
Charis EngGenomic Medicine Institute, Cleveland Clinic, Cleveland, OH.ORCID 0000-0002-3693-5145
Myriad Genetics · USCleveland Clinic · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose

methodsWe assessed a consecutive cohort of 727,091 individuals tested clinically for hereditary cancer risk, with a multigene panel between September 2013 and February 2022. Multivariable logistic regression models accounting for personal and family cancer history, age, sex, and ancestry were used to quantify disease risks associated with

results

conclusionWe demonstrate that

Indexed as

Breast NeoplasmsHamartoma Syndrome, MultipleThyroid NeoplasmsFemaleGenetic Predisposition to DiseaseHumansPhenotypePTEN PhosphohydrolasePTEN PhosphohydrolasePTEN protein, human

Identifiers

PMID36634299
PMCPMC9928870
OpenAlexW4315750681

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.