ArticleScience (New York, N.Y.)2023
Dome1-JAK-STAT signaling between parasite and host integrates vector immunity and development.
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In one paragraph
Article in Science (New York, N.Y.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
18.6field-weighted citation impact, top 1% of its field
What it found
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Who cites it
27 citing papers in PubMed, 52 citations in OpenAlex.
- The effects of IFNγ on tissue physiology through structural cells.Nature reviews. Immunology · 2026Review
- Cross-species TNF-α signaling in mosquitoes promotes malaria transmission.EMBO reports · 2026Article
- A non-canonical JAK/STAT pathway promotes viral replication through the lipoprotein receptor-related protein in ticks.PLoS biology · 2026Article
- Blood feeding triggers the terminal differentiation of precursor cells in tick salivary glands.Science advances · 2026Article
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- Targeting of interaction between BB0323-BB0238 informs new paradigms in Lyme disease therapeutics.PLoS pathogens · 2026Article
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- CCL17 Influences Borrelia burgdorferi Infection in the Heart.The Journal of infectious diseases · 2025Article
- Behavioral manipulation ofmBio · 2025Article
- Influence of blood feeding and infection on arthropod hemocytes.Current opinion in insect science · 2025Review
- Selective promotion of sensory innervation-mediated immunoregulation for tissue repair.Science advances · 2025Article
- Article
- Investigation of genes expression of the JAK/STAT signalling pathway and AMPs in the presence of Borrelia spirochetes in Ixodes ricinus.Scientific reports · 2025Article
- Article
- The Tick Microbiome: The "Other Bacterial Players" in Tick Biocontrol.Microorganisms · 2024Review
- High Crimean-Congo hemorrhagic fever incidence linked to greater genetic diversity and differentiation in Hyalomma marginatum populations in Türkiye.Parasites & vectors · 2024Article
- Vectorial dynamics underpinning current and future tick-borne virus emergence in Europe.The Journal of general virology · 2024Review
- Article
- Interferon-Science (New York, N.Y.) · 2024Review
- Tick hemocytes have a pleiotropic role in microbial infection and arthropod fitness.Nature communications · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
25 authors at 9 institutions in 2 countries.
Vipin S RanaDepartment of Veterinary Medicine, University of Maryland, College Park, MD, USA.ORCID 0000-0003-2673-7871
Chrysoula KitsouDepartment of Veterinary Medicine, University of Maryland, College Park, MD, USA.
Shraboni DuttaDepartment of Veterinary Medicine, University of Maryland, College Park, MD, USA.
Michael H RonzettiNational Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD, USA.ORCID 0000-0001-5034-7692
Min ZhangDepartment of Veterinary Medicine, University of Maryland, College Park, MD, USA.
Quentin BernardDepartment of Veterinary Medicine, University of Maryland, College Park, MD, USA.
Alexis A SmithDepartment of Veterinary Medicine, University of Maryland, College Park, MD, USA.
Julen Tomás-CortázarCIC bioGUNE-BRTA (Basque Research & Technology Alliance), 48160 Derio, Bizkaia, Spain.
Xiuli YangDepartment of Veterinary Medicine, University of Maryland, College Park, MD, USA.
Ming-Jie WuSection of Infectious Diseases, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT, USA.
Oleksandra KeppleDepartment of Veterinary Medicine, University of Maryland, College Park, MD, USA.ORCID 0000-0002-8123-3310
Weizhong LiDepartment of Veterinary Medicine, University of Maryland, College Park, MD, USA.
Jennifer E DwyerLaboratory of Cancer Biology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.ORCID 0000-0001-8029-849X
Jaqueline MatiasSection of Infectious Diseases, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT, USA.ORCID 0000-0002-8056-2825
Bolormaa BaljinnyamNational Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD, USA.ORCID 0000-0001-9548-4965
Jonathan D OliverDepartment of Entomology, University of Minnesota, Minneapolis, MN, USA.
Nallakkandi RajeevanYale Center for Medical Informatics, Yale University School of Medicine, New Haven, CT, USA.
Joao H F PedraDepartment of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, MD, USA.ORCID 0000-0001-8740-2667
Sukanya NarasimhanSection of Infectious Diseases, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT, USA.ORCID 0000-0003-0396-8757
Yan WangMass Spectrometry Facility, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, MD, USA.ORCID 0000-0003-1187-9527
Ulrike MunderlohDepartment of Entomology, University of Minnesota, Minneapolis, MN, USA.ORCID 0000-0001-7935-2874
Erol FikrigSection of Infectious Diseases, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT, USA.ORCID 0000-0002-5884-6047
Anton SimeonovNational Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD, USA.ORCID 0000-0002-4523-9977
Juan AnguitaCIC bioGUNE-BRTA (Basque Research & Technology Alliance), 48160 Derio, Bizkaia, Spain.ORCID 0000-0003-2061-7182
Utpal PalDepartment of Veterinary Medicine, University of Maryland, College Park, MD, USA.ORCID 0000-0002-7504-4628
University of Maryland, College Park · USNational Institutes of Health · USYale University · USUniversity of Minnesota · USCIC bioGUNE · ESHoward Hughes Medical Institute · USIkerbasque · ESUniversity of Maryland, Baltimore · USVirginia–Maryland College of Veterinary Medicine · US
Funding
Tick Resources CoreP01AI138949 · NIAID · UNIV OF MARYLAND, COLLEGE PARK · PI Erol Fikrig, UTPAL PAL · 2018 to 2026
$13.5MUbiquitylation and Rickettsial Colonization of a Tick VectorR01AI116523 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI PEDRA, JOAO · 2016 to 2025
$6.2MBORRELIA GENE PRODUCTS CRITICAL FOR NATURAL INFECTION CYCLER01AI080615 · NIAID · UNIV OF MARYLAND, COLLEGE PARK · PI PAL, UTPAL · 2009 to 2024
$5.2MTick Saliva and Pathogen TransmissionR01AI134696 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI Joao Pedra · 2018 to 2026
$5.1MMass Spectrometry FacilityZICDE000751 · NIDCR · NATIONAL INSTITUTE OF DENTAL & CRANIOFACIAL RESEARCH · PI WANG, YAN · 2020 to 2025
$3.6MMultivalent Tick-Microbe targeted Lyme disease vaccinesR01AI154542 · NIAID · UNIV OF MARYLAND, COLLEGE PARK · PI PAL, UTPAL, SCHNELL, MATTHIAS JOHANNES · 2020 to 2025
$3.5MA novel Lyme disease vaccineR01AI165499 · NIAID · YALE UNIVERSITY · PI CRAFT, JOSEPH EDGAR, FIKRIG, EROL · 2022 to 2025
$3.2MBBA57-Mediated Borrelial Persistence, Genesis of Inflammation and ImmunityR01AI116620 · NIAID · UNIV OF MARYLAND, COLLEGE PARK · PI PAL, UTPAL · 2015 to 2019
$1.9MScreening for B. burgdorferi borreliacidal/borreliastatic compoundsZIATR000413 · NCATS · NATIONAL CENTER FOR ADVANCING TRANSLATIONAL SCIENCES · PI MARTINEZ, NATALIA · 2020 to 2025
$1.4MBorella Gene Products Critical For Natural Infection CycleR56AI080615 · NIAID · UNIV OF MARYLAND, COLLEGE PARK · PI PAL, UTPAL · 2013 to 2013
$357kMass Spectrometry FacilityZIADE000751 · NIDCR · NATIONAL INSTITUTE OF DENTAL & CRANIOFACIAL RESEARCH · PI WANG, YAN · 2019 to 2019
$193kIntramural NIH HHS ZIA DE000751Intramural NIH HHS ZIA TR000413NIAID NIH HHS P01 AI138949NIAID NIH HHS R01 AI080615NIAID NIH HHS R01 AI116523NIAID NIH HHS R01 AI116620NIAID NIH HHS R01 AI134696NIAID NIH HHS R01 AI154542NIAID NIH HHS R01 AI165499NIAID NIH HHS R56 AI080615
Abstract
Ancestral signaling pathways serve critical roles in metazoan development, physiology, and immunity. We report an evolutionary interspecies communication pathway involving a central
Indexed as
Arachnid VectorsHost-Parasite InteractionsIxodesJanus KinasesReceptors, CytokineSTAT Transcription FactorsAnimalsInterferon-gammaSignal TransductionInterferon-gammaJanus KinasesReceptors, CytokineSTAT Transcription Factors
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.