Evidence map›Paper›PMID 36633921›Full record

ArticleThyroid : official journal of the American Thyroid Association2023

Congenital Hypothyroidism in Two Sudanese Families Harboring a Novel Iodotyrosine Deiodinase Mutation (IYD R279C).

Reham Shareef, Aryel Furman, Yui Watanabe, Ryan Bruellman, Mohammed A Abdullah, Alexandra M Dumitresu, Samuel Refetoff, Andrea Bertolini, Marco Borsò, Alessandro Saba and 2 more

Open access · greenAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Thyroid : official journal of the American Thyroid Association, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Approach to the patient: genetics and management of congenital hypothyroidism.The Journal of clinical endocrinology and metabolism · 2026
    Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 3 countries.

Reham ShareefDepartment of Pediatrics and Child Health, Faculty of Medicine, University of AlMughatribeen, Khartoum, Sudan.
Aryel FurmanDepartment of Medicine; University of Miami Miller School of Medicine, Miami, Florida, USA.
Yui WatanabeDepartment of Medicine; University of Miami Miller School of Medicine, Miami, Florida, USA.
Ryan BruellmanDepartment of Medicine; University of Miami Miller School of Medicine, Miami, Florida, USA.
Mohammed A AbdullahDepartment of Pediatrics and Child Health, Faculty of Medicine, University of Khartoum, Khartoum, Sudan.
Alexandra M DumitresuDepartment of Medicine, The University of Chicago, Chicago, Illinois, USA.ORCID 0000-0002-2743-770X
Samuel RefetoffDepartment of Medicine, The University of Chicago, Chicago, Illinois, USA.ORCID 0000-0003-0164-8231
Andrea BertoliniDepartment of Surgical, Medical and Molecular Pathology and Critical Care Medicine, University of Pisa, Pisa, Italy.
Marco BorsòDepartment of Surgical, Medical and Molecular Pathology and Critical Care Medicine, University of Pisa, Pisa, Italy.ORCID 0000-0001-7467-7960
Alessandro SabaDepartment of Surgical, Medical and Molecular Pathology and Critical Care Medicine, University of Pisa, Pisa, Italy.
Riccardo ZucchiDepartment of Surgical, Medical and Molecular Pathology and Critical Care Medicine, University of Pisa, Pisa, Italy.
Roy E WeissDepartment of Medicine; University of Miami Miller School of Medicine, Miami, Florida, USA.
University of Miami · USUniversity of Pisa · ITUniversity of Chicago · USAlMughtaribeen University · SDUniversity of Khartoum · SD

Funding

THYROID PHYSIOLOGY STUDIES OF INHERITED DISORDERSR01DK015070 · NIDDK · UNIVERSITY OF CHICAGO · PI ANTONIO C BIANCO, Alexandra Mihaela Dumitrescu · 1986 to 2026
$8.1M
Mouse Sbp2 deficiency models the multi-system syndrome of human SBP2 defectsR01DK110322 · NIDDK · UNIVERSITY OF CHICAGO · PI DUMITRESCU, ALEXANDRA MIHAELA · 2016 to 2020
$1.8M
NIDDK NIH HHS R01 DK015070NIDDK NIH HHS R01 DK110322
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Congenital HypothyroidismDiiodotyrosineMutationHumansIodide PeroxidaseMonoiodotyrosineDiiodotyrosineIodide PeroxidaseMonoiodotyrosinecongenital hypothyroidismdehalogenasegoiteriodine deficiencyiodotyrosine deiodinasemonoiodotyrosine

Identifiers

PMID36633921
PMCPMC9963472
OpenAlexW4315754144

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.