ArticleGeroScience2023
Growth hormone receptor (GHR) in AgRP neurons regulates thermogenesis in a sex-specific manner.
Article in GeroScience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 16 citations in OpenAlex.
- The suprachiasmatic nucleus: a central pacemaker for temporal coordination of energy metabolic homeostasis.Reviews in endocrine & metabolic disorders · 2026Review
- Thermogenic adipose tissue in older adults with obesity: a narrative review of mechanisms, brown fat resistance, and the translational relevance of exercise and nutrition.Frontiers in nutrition · 2026Review
- Aging reveals divergent responses of AgRP/NPY neurons to diet in male and female mice.bioRxiv : the preprint server for biology · 2025Article
- Liver injury severity determines skeletal deterioration: a shared pathophysiological axis between MASLD and osteoarthritis.GeroScience · 2025Article
- Microglial ER stress response via IRE1α regulates diet-induced metabolic imbalance and obesity in mice.Molecular metabolism · 2025Article
- Growth Hormone, Hypothalamic Inflammation, and Aging.Journal of obesity & metabolic syndrome · 2024Review
- Growth hormone receptor in VGLUT2 or Sim1 cells regulates glycemia and insulin sensitivity.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Growth Hormone Receptor in Lateral Hypothalamic Neurons Is Required for Increased Food-Seeking Behavior during Food Restriction in Male Mice.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- New findings on brain actions of growth hormone and potential clinical implications.Reviews in endocrine & metabolic disorders · 2024Review
- The Pattern of GH Action in the Mouse Brain.Endocrinology · 2024Article
- Editorial: Endocrine regulation of aging: impacts of humoral factors and circulating mediators.Frontiers in endocrinology · 2024Article
- Article
- Growth Hormone Action in Somatostatin Neurons Regulates Anxiety and Fear Memory.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
- Central growth hormone action regulates neuroglial and proinflammatory markers in the hypothalamus of male mice.Neuroscience letters · 2023Article
Corrections and comments
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Authors and funding
9 authors at 4 institutions in 2 countries.
Funding
Abstract
Evidence for hypothalamic regulation of energy homeostasis and thermoregulation in brown adipose tissue (BAT) during aging has been well recognized, yet the central molecular mediators involved in this process are poorly understood. The arcuate hypothalamus, orexigenic agouti-related peptide (AgRP) neurons control nutrient intake, energy homeostasis, and BAT thermogenesis. To determine the roles of growth hormone receptor (GHR) signaling in the AgRP neurons, we used mice with the AgRP-specific GHR deletion (AgRP
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.