Evidence map›Paper›PMID 36633567›Full record

ArticlePublic health nursing (Boston, Mass.)

Correlates of SARS-CoV-2 anti-RBD IgG antibody titers among persons experiencing homelessness in Los Angeles.

Adeline Nyamathi, Sanghyuk S Shin, Brianna M Doratt, Alexandria Jones-Patten, Benissa Salem, Lillian Gelberg, Darlene Lee, Dana Garfin, Kartik Yadav, Alicia H Chang and 3 more

Open access · hybridAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Public health nursing (Boston, Mass.). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 1 country.

Adeline NyamathiSue & Bill Gross School of Nursing, University of California, Irvine, California.
Sanghyuk S ShinSue & Bill Gross School of Nursing, University of California, Irvine, California.
Brianna M DorattMicrobiology, Immunology, and Molecular Genetics, College of Medicine, University of Kentucky, Lexington, Kentucky.ORCID 0000-0002-8107-724X
Alexandria Jones-PattenSue & Bill Gross School of Nursing, University of California, Irvine, California.
Benissa SalemSchool of Nursing, University of California, Los Angeles, California.
Lillian GelbergDavid Geffen School of Medicine, University of California, Los Angeles, California.
Darlene LeeSusan Samueli Integrative Health Institute, University of California Irvine, Irvine, California.
Dana GarfinSue & Bill Gross School of Nursing, University of California, Irvine, California.
Kartik YadavSue & Bill Gross School of Nursing, University of California, Irvine, California.
Alicia H ChangLos Angeles County Department of Public Health, Community & Field Services, Los Angeles, California.
Kathryn WhiteLos Angeles Christian Health Center, Health Center, Los Angeles, California.
Nicholas ArceSchool of Social Ecology, University of California, Irvine, California.
Ilhem MessaoudiMicrobiology, Immunology, and Molecular Genetics, College of Medicine, University of Kentucky, Lexington, Kentucky.
University of California, Irvine · USLos Angeles County Department of Public Health · USUniversity of California, Los Angeles · USUniversity of Kentucky · US

Funding

Impact of chronic ethanol consumption on lung functional and immunological landscape and implication for susceptibility to SARSCoV2 infectionR01AA028735 · NIAAA · UNIVERSITY OF KENTUCKY · PI MESSAOUDI, ILHEM, VARLAMOV, OLEG · 2020 to 2025
$4.4M
NIAAA NIH HHS R01 AA028735
6 · The paper itself

Abstract

objectivesPeople experiencing homelessness (PEH) have been especially impacted by the COVID-19 pandemic, likely due to increased vulnerabilities stemming from chronic diseases, substance use, and mental health conditions.

designA case-control study to assess the presence of antibodies against SARS-CoV-2 among PEH and associations with key variables. SAMPLE: A convenience sample of 97 PEH in Skid Row, Los Angeles. MEASUREMENTS: A structured questionnaire assessing socio-demographic, mental health, drug and alcohol use, health care access, pandemic stress, and other COVID-19-specific questions.

resultsWe found high anti-receptor binding domain (RBD) IgG titers among five of 15 PEH who reported no prior COVID-19 diagnosis or being vaccinated, suggesting undiagnosed and/or asymptomatic COVID-19. While anti-RBD IgG titers across vaccination categories were not statistically significant (p = .069), participants vaccinated with Janssen had the lowest mean anti-RBD IgG titers. In multivariable analysis, we found negative associations between level of SARS-CoV-2 antibody titers with the Janssen vaccine and depression; thus, a need for integrated care for PEH with depression and COVID-19.

conclusionsFurther research is warranted to confirm the immune response, initial and over time, to SARS-CoV-2 infection and to COVID-19 vaccinations, particularly among PEH whose immune systems may be impacted by multiple health conditions.

Indexed as

COVID-19Ill-Housed PersonsAntibodies, ViralCase-Control StudiesCOVID-19 TestingCross-Sectional StudiesHumansImmunoglobulin GLos AngelesMultimorbidityPandemicsSARS-CoV-2Antibodies, ViralImmunoglobulin Gpeople experiencing homelessnessSARS-CoV-2 antibody seroprevalencesubstance use

Identifiers

PMID36633567
PMCPMC10210586
OpenAlexW4315754385

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.