Evidence map›Paper›PMID 36633543›Full record

ReviewJournal of industrial microbiology & biotechnology2023

Natural promoters and promoter engineering strategies for metabolic regulation in Saccharomyces cerevisiae.

Shifan He, Zhanwei Zhang, Wenyu Lu

Abstract readReview
In one paragraph

Review in Journal of industrial microbiology & biotechnology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Synthetic and systems biotechnology · 2026
    Article
  2. Article
  3. Review
  4. Article
  5. CRISPR-based synthetic biology toolkit development inSynthetic and systems biotechnology · 2026
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Multi-step pathway engineering in probioticMetabolic engineering communications · 2025
    Article
  12. Review
  13. Article
  14. Effect ofAnimals : an open access journal from MDPI · 2025
    Article
  15. Review
  16. Article
  17. Review
  18. Genetic tools for metabolic engineering ofEngineering microbiology · 2023
    Review
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Shifan HeSchool of Chemical Engineering and Technology, Tianjin University, Tianjin 300350, PR China.
Zhanwei ZhangSchool of Chemical Engineering and Technology, Tianjin University, Tianjin 300350, PR China.
Wenyu LuSchool of Chemical Engineering and Technology, Tianjin University, Tianjin 300350, PR China.ORCID 0000-0002-3093-3990

Funding

Key-Area Research and Development Program of Guangdong Province 2020B0303070002National Key Research and Development Program of China 2019YFA0905100
6 · The paper itself

Abstract

Sharomyces cerevisiae is currently one of the most important foreign gene expression systems. S. cerevisiae is an excellent host for high-value metabolite cell factories due to its advantages of simplicity, safety, and nontoxicity. A promoter, as one of the basic elements of gene transcription, plays an important role in regulating gene expression and optimizing metabolic pathways. Promoters control the direction and intensity of transcription, and the application of promoters with different intensities and performances will largely determine the effect of gene expression and ultimately affect the experimental results. Due to its significant role, there have been many studies on promoters for decades. While some studies have explored and analyzed new promoters with different functions, more studies have focused on artificially modifying promoters to meet their own scientific needs. Thus, this article reviews current research on promoter engineering techniques and related natural promoters in S. cerevisiae. First, we introduce the basic structure of promoters and the classification of natural promoters. Then, the classification of various promoter strategies is reviewed. Finally, by grouping related articles together using various strategies, this review anticipates the future development direction of promoter engineering.

Indexed as

Saccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsGene Expression Regulation, FungalMetabolic EngineeringMetabolic Networks and PathwaysPromoter Regions, GeneticSaccharomyces cerevisiae ProteinsBiosensorGene expressionPromotersSaccharomyces cerevisiae

Identifiers

PMID36633543
PMCPMC9936215

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.