Evidence map›Paper›PMID 36633453›Full record

ArticleDeutsches Arzteblatt international2023

Mortality With and Without Whole-Body CT in Severely Injured Children.

Mathias Berger, Rolf Lefering, Michael Bauer, Gunther O Hofmann, Stefan Reske, Peter Hilbert-Carius, DGU Trauma Registry

Abstract read
In one paragraph

Article in Deutsches Arzteblatt international, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mathias BergerUniversity Hospitals of Friedrich-Schiller-University Jena and Department of Anesthesiology and Intensive Care Medicine, Elisabeth-Hospital Halle (Saale); Institute for Research in Operative Medicine (IFOM) Cologne Campus Merheim, Witten/Herdecke University; Department of Anesthesiology and Intensive Care Medicine, University Hospitals of Friedrich-Schiller-University Jena; Clinic for Trauma-, Handand Reconstructive Surgery, University Hospitals of Friedrich-Schiller-University Jena and Clinic for Traumaand Reconstructive Surgery, Bergmannstrost BG-Hospital Halle (Saale); Institute of Diagnostic and Interventional Radiology and Neuroradiology, Heinrich-Braun-Clinic Zwickau; Department of Anesthesiology, Intensive Care, Bergmannstrost BG-Hospital Halle (Saale).
Rolf Lefering
Michael Bauer
Gunther O Hofmann
Stefan Reske
Peter Hilbert-Carius
DGU Trauma Registry

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe choice of imaging modality-the use of whole-body computed tomography (WB-CT) versus a step-wise diagnostic procedure-in injured children is controversial. In this study we availed ourselves of data from the TR-DGU, the trauma registry of the German Society for Trauma Surgery (Deutsche Gesellschaft für Unfallchirurgie), to investigate whether the use of WB-CT improves the outcome.

methodsThe TR-DGU data from the period 2012-2021 were evaluated. A three-stage analysis began with comparison of children with adults aged ≤ 50 years. As a second step, the observed and expected mortality in children with WB-CT was compared with the mortality in children without WB-CT. Finally, predictors of the use of WB-CT were identified so that a propensity score analysis of matched pairs could be performed.

resultsA total of 65 092 patients were included, 4573 children (7%) and 60 519 adults (93%), with differences in accident type and injury pattern. Comparison of the ratio of observed to expected mortality revealed no difference between the two groups of children (standardized mortality ratio 0.97 with WB-CT, 0.95 without WB-CT). In adults, however, there was an advantage for the WB-CT group. The propensity score analysis of 1101 matched pairs showed identical mortality in the two groups (3.9% with WB-CT, 4.0% without WB-CT).

conclusionThe TR-DGU data show no benefit of WB-CT compared with step-wise diagnosis in the care of severely injured children. In view of the radiation exposure involved, with the danger of inducing malignancy, the benefits and risks of the use of WB-CT in children should be weighed up carefully in team discussions.

Indexed as

Multiple TraumaAdultChildHospital MortalityHumansInjury Severity ScoreRegistriesTomography, X-Ray Computed

Identifiers

PMID36633453
PMCPMC10213478

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.