Evidence map›Paper›PMID 36633418›Full record

Observational studyBJS open2023

Surgical site infections after emergency hernia repair: substudy from the Management of Acutely Symptomatic Hernia (MASH) study.

Victoria K Proctor, Olivia M O'Connor, Flora A Burns, Susie Green, Adele E Sayers, Deborah J Hawkins, Neil J Smart, Matthew J Lee, MASH Collaborators

Registry-linked trialOpen access · goldAbstract readMulticenter StudyObservational Study
In one paragraph

Observational study in BJS open, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04197271 (Management of Acutely Symptomatic Hernia), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04197271 completednot on this map

Management of Acutely Symptomatic Hernia: An Observational Study

TypeobservationalSponsorSheffield Teaching Hospitals NHS Foundation TrustRan2020 to 2021Enrolled280ConditionsHernia, Emergencies, Surgery--ComplicationsArmsEmergency Hernia Repair, Conservative management
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Victoria K ProctorAcademic Directorate of General Surgery, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK.ORCID 0000-0001-6720-6773
Olivia M O'ConnorAcademic Directorate of General Surgery, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK.
Flora A BurnsAcademic Directorate of General Surgery, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK.
Susie GreenDepartment of General Surgery, York Teaching Hospitals, York, UK.
Adele E SayersAcademic Directorate of General Surgery, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK.ORCID 0000-0001-8561-4834
Deborah J HawkinsAcademic Directorate of General Surgery, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK.
Neil J SmartDepartment of General Surgery, Royal Devon and Exeter Hospital, Exeter, UK.
Matthew J LeeAcademic Directorate of General Surgery, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK.ORCID 0000-0001-9971-1635
MASH Collaborators
Sheffield Teaching Hospitals NHS Foundation Trust · GBRoyal Devon and Exeter Hospital · GBYork Teaching Hospital NHS Foundation Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAcutely symptomatic abdominal wall and groin hernias (ASH) are a common acute surgical presentation. There are limited data to guide decisions related to surgical repair technique and use of antibiotics, which can be driven by increased risk of surgical site infection (SSI) in this group. This study aims to report rates of SSI following ASH repair and explore the use of patient-reported outcome measure reporting in this setting.

methodsAn 18-week, UK-based, multicentre prospective cohort study (NCT04197271) recruited adults with ASH. This study reports operatively managed patients. Data on patient characteristics, inpatient management, quality of life, complications, and wound healing (Bluebelle score) were collected. Descriptive analyses were performed to estimate event rates of SSI and regression analysis explored the relationship between Bluebelle scores and SSI. The 30 and 90-day follow-up visits assessed complications and quality of life.

resultsThe MASH study recruited 273 patients, of whom 218 were eligible for this study, 87.2 per cent who underwent open repair. Mesh was used in 123 patients (50.8 per cent). Pre- and postoperative antibiotics were given in 163 (67.4 per cent) and 28 (11.5 per cent) patients respectively. There were 26 reported SSIs (11.9 per cent). Increased BMI, incisional, femoral, and umbilical hernia were associated with higher rates of SSI (P = 0.006). In 238 patients, there was a difference in healthy utility values at 90 days between patients with and without SSI (P = 0.025). Also, when analysing 191 patients with Bluebelle scores, those who developed an SSI had higher Bluebelle values (P < 0.001).

conclusionSSI is frequent in repair of acutely symptomatic hernia and correlates with BMI and site of hernia.

Indexed as

Emergency Medical ServicesHerniorrhaphySurgical Wound InfectionAdultAnti-Bacterial AgentsHumansPatient Reported Outcome MeasuresProspective StudiesQuality of LifeRisk FactorsUnited KingdomAnti-Bacterial Agents

Identifiers

PMID36633418
PMCPMC9835494
OpenAlexW4315752497

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.