Evidence map›Paper›PMID 36633416›Full record

ArticleInfection and immunity2023

A Positively Selected

John T Loh, Emily L Struttmann, Natalie Favret, M Lorena Harvey, Suman B Pakala, Abha Chopra, Mark S McClain, Timothy L Cover

Abstract read
In one paragraph

Article in Infection and immunity, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Microbiology and molecular biology reviews : MMBR · 2026
    Review
  2. Multiple TonB-dependent transport systems inInfection and immunity · 2026
    Article
  3. Review
  4. Article
  5. Essential role ofInfection and immunity · 2023
    Article
  6. High-Salt Diet ExacerbatesJournal of personalized medicine · 2023
    Review
  7. Clinical Pathogenesis, Molecular Mechanisms of Gastric Cancer Development.Current topics in microbiology and immunology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

John T LohDepartment of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.
Emily L StruttmannDepartment of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.
Natalie FavretDepartment of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
M Lorena HarveyDepartment of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Suman B PakalaDepartment of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.
Abha ChopraInstitute for Immunology and Infectious Diseases, Murdoch University, Murdoch, Australia.
Mark S McClainDepartment of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.ORCID 0000-0002-9857-4883
Timothy L CoverDepartment of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.ORCID 0000-0001-8503-002X

Funding

Tumor Immunology and Microenvironment Research ProgramP30CA068485 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI STACIE B DUSETZINA · 1995 to 2026
$172.8M
Role of Iron and B-Catenin Activation in Gastric CarcinogenesisP01CA116087 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI RICHARD M. PEEK · 2009 to 2026
$27.5M
Structure-function analysis of H. pylori VacAR01AI039657 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI TIMOTHY L COVER · 1996 to 2026
$8.3M
Type IV Protein Secretion in Helicobacter pyloriR01AI118932 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI COVER, TIMOTHY L, OHI, MELANIE DIANE · 2016 to 2025
$6.7M
"Pathogenesis of Helicobacter pylori Infection"I01BX004447 · VA · VETERANS HEALTH ADMINISTRATION · PI TIMOTHY L COVER · 2019 to 2026
–
BLRD VA I01 BX004447NCI NIH HHS P01 CA116087NCI NIH HHS P30 CA068485NIAID NIH HHS R01 AI039657NIAID NIH HHS R01 AI118932
6 · The paper itself

Abstract

Both Helicobacter pylori infection and a high-salt diet are risk factors for gastric cancer. We previously showed that a mutation in

Indexed as

Bacterial ProteinsHelicobacter pyloriRepressor ProteinsGene Expression Regulation, BacterialHelicobacter InfectionsHumansMutationSodium ChlorideBacterial ProteinsRepressor ProteinsSodium Chlorideevolutionevolutionary biologyfitnessgene regulationpositive selectiontranscriptional regulation

Identifiers

PMID36633416
PMCPMC9933627

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.