Evidence map›Paper›PMID 36633137›Full record

ArticleMolecular medicine reports2023

SPARC is a decoy counterpart for c‑Fos and is associated with osteoblastic differentiation of bone marrow stromal cells by inhibiting adipogenesis.

Tomoya Hatori, Toyonobu Maeda, Atsuko Suzuki, Keiso Takahashi, Yasumasa Kato

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecular medicine reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

  1. Cellular and molecular mechanisms of fatty infiltration in paraspinal muscles in spine-specific sarcopenia.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2026
    Review
  2. Article
  3. Article
  4. Sword Bean (Nutrients · 2023
    Article
  5. Osteonectin bidirectionally regulates osteoblast mineralization.Journal of orthopaedic surgery and research · 2023
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Tomoya HatoriDepartment of Oral Physiology and Biochemistry, Ohu University Graduate School of Dentistry, Koriyama, Fukushima 963‑8611, Japan.
Toyonobu MaedaDepartment of Oral Physiology and Biochemistry, Ohu University Graduate School of Dentistry, Koriyama, Fukushima 963‑8611, Japan.
Atsuko SuzukiDepartment of Oral Physiology and Biochemistry, Ohu University Graduate School of Dentistry, Koriyama, Fukushima 963‑8611, Japan.
Keiso TakahashiDepartment of Conservative Dentistry, Ohu University School of Dentistry, Koriyama, Fukushima 963‑8611, Japan.
Yasumasa KatoDepartment of Oral Physiology and Biochemistry, Ohu University Graduate School of Dentistry, Koriyama, Fukushima 963‑8611, Japan.
Ohu University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Secreted protein acidic and rich in cysteine (SPARC), also called basement‑membrane protein 40 or osteonectin, is a matricellular protein that is abundant not only in bone tissue as a non‑collagenous protein but is also ubiquitously expressed in non‑calcified tissue. SPARC is located intracellularly and disruption of the

Indexed as

Mesenchymal Stem CellsOsteonectinAdipogenesisCell DifferentiationInterleukin-1 Receptor-Like 1 ProteinProtein Sorting SignalsProto-Oncogene Proteins c-fosTranscription Factor AP-1Interleukin-1 Receptor-Like 1 ProteinOsteonectinProtein Sorting SignalsProto-Oncogene Proteins c-fosTranscription Factor AP-1activator protein‑1 activityadipogenesisc‑Fosdecoyosteoblastogenesissecreted protein acidic and rich in cysteine

Identifiers

PMID36633137
PMCPMC9879077
OpenAlexW4313909737

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.