Evidence map›Paper›PMID 36632893›Full record

ArticleInternational journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases2023

The in-hospital tuberculosis diagnostic cascade and early clinical outcomes among people living with HIV before and during the COVID-19 pandemic - a prospective multisite cohort study from Ghana.

Johanna Åhsberg, Stephanie Bjerrum, Vincent Jessey Ganu, Augustine Kwashie, Joseph Oliver Commey, Yaw Adusi-Poku, Peter Puplampu, Åse Bengård Andersen, Ernest Kenu, Margaret Lartey and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.0field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 2 countries.

Johanna ÅhsbergDepartment of Infectious diseases, Odense University Hospital, Odense, Denmark; International Reference Laboratory of Mycobacteriology, Statens Serum Institut, Copenhagen, Denmark; Mycobacterial Centre for Research Southern Denmark MyCRESD, Odense University Hospital, Odense, Denmark; Department of Clinical research, University of Southern Denmark, Odense, Denmark. Electronic address: johanna.maria.aahsberg@rsyd.dk.
Stephanie BjerrumDepartment of Infectious diseases, Odense University Hospital, Odense, Denmark; Mycobacterial Centre for Research Southern Denmark MyCRESD, Odense University Hospital, Odense, Denmark; Department of Infectious Diseases, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark.
Vincent Jessey GanuDepartment of Medicine, Korle-Bu Teaching Hospital, Accra, Ghana.
Augustine KwashieDepartment of Medicine, Tema General Hospital, Tema, Ghana.
Joseph Oliver CommeyDepartment of Medicine, Lekma Hospital, Teshie, Ghana.
Yaw Adusi-PokuNational Tuberculosis Control Programme, Ghana Health Service, Accra, Ghana.
Peter PuplampuDepartment of Medicine & Therapeutics, Medical school, College of Health sciences, University of Ghana, Accra, Ghana.
Åse Bengård AndersenDepartment of Infectious Diseases, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark.
Ernest KenuDepartment of Epidemiology and Disease control, University of Ghana, Accra, Ghana.
Margaret LarteyDepartment of Medicine & Therapeutics, Medical school, College of Health sciences, University of Ghana, Accra, Ghana.
Isik Somuncu JohansenDepartment of Infectious diseases, Odense University Hospital, Odense, Denmark; Mycobacterial Centre for Research Southern Denmark MyCRESD, Odense University Hospital, Odense, Denmark; Department of Clinical research, University of Southern Denmark, Odense, Denmark.
University of Ghana · GHUniversity of Southern Denmark · DKCopenhagen University Hospital · DKGhana Health Service · GHKorle Bu Teaching Hospital · GHStatens Serum Institut · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe COVID-19 pandemic had a disruptive impact on tuberculosis (TB) and HIV services. We assessed the in-hospital TB diagnostic care among people with HIV (PWH) overall and before and during the pandemic.

methodsIn this prospective study, adult PWH admitted at three hospitals in Ghana were recruited if they had a positive World Health Organization four-symptom screen or one or more World Health Organization danger signs or advanced HIV. We collected data on patient characteristics, TB assessment, and clinical outcomes after 8 weeks and used descriptive statistics and survival analysis.

resultsWe enrolled 248 PWH with a median clusters of differentiation 4 count of 80.5 cells/mm

conclusionThe study highlighted a large gap in the access to TB investigation and high early mortality among hospitalized PWH, irrespective of the COVID-19 pandemic.

Indexed as

COVID-19HIV InfectionsMycobacterium tuberculosisTuberculosisAdultCohort StudiesCOVID-19 TestingGhanaHospitalsHumansPandemicsProspective StudiesSensitivity and SpecificitySputumCare cascadeCOVID-19DiagnosisHIVTuberculosisXpert MTB/RIF

Identifiers

PMID36632893
PMCPMC9827749
OpenAlexW4313830809

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.