Evidence map›Paper›PMID 36632743›Full record

ArticleEuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology2023

Impact of periprocedural major adverse events on 10-year mortality after revascularisation.

Nozomi Kotoku, Patrick W Serruys, Kai Ninomiya, Alan Soo, Shinichiro Masuda, Shigetaka Kageyama, Pruthvi C Revaiah, Michael J Mack, David R Holmes, Marie-Claude Morice and 6 more

Open access · greenAbstract read
In one paragraph

Article in EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Revascularisation, periprocedural events and survival - and the survival of the randomised controlled trial.EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology · 2023
    Trial
  2. Clinical Impact of Angiographic Complications Occurring During Percutaneous Coronary Interventions.Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2026
    Article
  3. Periprocedural adverse events after revascularisation: the importance of getting off to a good start.EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 8 institutions in 7 countries.

Nozomi KotokuDepartment of Cardiology, University of Galway, Galway, Ireland.
Patrick W SerruysDepartment of Cardiology, University of Galway, Galway, Ireland.
Kai NinomiyaDepartment of Cardiology, University of Galway, Galway, Ireland.
Alan SooDepartment of Cardiothoracic Surgery, University Hospital Galway, Galway, Ireland.
Shinichiro MasudaDepartment of Cardiology, University of Galway, Galway, Ireland.
Shigetaka KageyamaDepartment of Cardiology, University of Galway, Galway, Ireland.
Pruthvi C RevaiahDepartment of Cardiology, University of Galway, Galway, Ireland.
Michael J MackDepartment of Cardiothoracic Surgery, Baylor Scott & White Health, Dallas, TX, USA.
David R HolmesDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, USA.
Marie-Claude MoriceUnité de Cardiologie, Hôpital Privé Jacques Cartier, Ramsay Générale de Santé, Massy, France.
Piroze M DavierwalaUniversity Department of Cardiac Surgery, Heart Centre Leipzig, Leipzig, Germany.
Friedrich W MohrUniversity Department of Cardiac Surgery, Heart Centre Leipzig, Leipzig, Germany.
Milan MilojevicDepartment of Cardiothoracic Surgery, Erasmus University Medical Centre, Rotterdam, the Netherlands.
Arie Pieter KappeteinDepartment of Cardiothoracic Surgery, Erasmus University Medical Centre, Rotterdam, the Netherlands.
Scot GargDepartment of Cardiology, Royal Blackburn Hospital, Blackburn, UK.
Yoshinobu OnumaDepartment of Cardiology, University of Galway, Galway, Ireland.
Ollscoil na Gaillimhe – University of Galway · IEErasmus University Rotterdam · NLBaylor Scott & White Health · USLeipzig Heart Institute · DEMayo Clinic in Arizona · USRoyal Blackburn Teaching Hospital · GBUniversity Hospital Galway · IEUniversity of Toronto · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe long-term prognostic impact of a composite of periprocedural major adverse events (PMAE) following revascularisation for patients with complex coronary artery disease (CAD) has not yet been established.

aimsThis study aimed to assess the impact on 10-year mortality of non-fatal PMAE following percutaneous coronary intervention (PCI) or coronary artery bypass grafting (CABG). Other objectives were to evaluate 1) whether PMAE affect mortality predicted by the SYNTAX score II 2020 (SSII-2020) and 2) whether optimal medical therapy (OMT) positively affects the prognosis of patients with non-fatal PMAE.

methodsThe association between 10-year mortality and non-fatal PMAE occurring within 30 days of PCI or CABG in patients with three-vessel disease and/or left main disease enrolled in the SYNTAXES study was investigated.

resultsThe main findings are that non-fatal PMAE occurred less frequently following PCI than CABG (11.2% vs 28.2%; p<0.001) and that non-fatal PMAE were an independent predictor of all-cause mortality in the first year post-procedure, but not at 5 or 10 years, in both treatment modalities. PMAE substantially alter the individual predictions of 10-year mortality by the SSII-2020. In patients with non-fatal PMAE, OMT may provide survival benefits during the first year post-procedure as well as in the long term.

conclusionsIn patients with complex CAD, non-fatal PMAE were more common following CABG than PCI, but their prognostic impact was similar, being significant in the first year and then diminishing out to 10 years. Patients with non-fatal PMAE may therefore require more careful follow-up and additional preventive treatment in the first year post-procedure.

Indexed as

Coronary Artery DiseaseDrug-Eluting StentsPercutaneous Coronary InterventionCoronary Artery BypassHumansPrognosisTreatment Outcome

Identifiers

PMID36632743
PMCPMC10018290
OpenAlexW4315752847

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.