Evidence map›Paper›PMID 36632684›Full record

ArticleBlood research2023

Abnormal expression of

Jorge Antonio Zamora Dominguez, Irma Olarte Carrillo, Rubén Ruiz Ramos, Christian Omar Ramos-Peñafiel, Luis Jiménez Zamudio, Ethel García Latorre, Federico Centeno Cruz, Adolfo Martínez Tovar

Open access · diamondAbstract read
In one paragraph

Article in Blood research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Diallyl disulfide in oncotherapy: molecular mechanisms and therapeutic potentials.Apoptosis : an international journal on programmed cell death · 2025
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Jorge Antonio Zamora DominguezLaboratorio de Biología Molecular, Servicio de Hematología, Hospital General de México, Dr. Eduardo Liceaga, Ciudad de México Molecular Biology Laboratory, Ciudad de México, México.
Irma Olarte CarrilloLaboratorio de Biología Molecular, Servicio de Hematología, Hospital General de México, Dr. Eduardo Liceaga, Ciudad de México Molecular Biology Laboratory, Ciudad de México, México.
Rubén Ruiz RamosFacultad de Medicina, Universidad Veracruzana, Veracruz, México.
Christian Omar Ramos-PeñafielServicio de Hematología, Hospital General de México Dr. Eduardo Liceaga, México.
Luis Jiménez ZamudioLaboratorio de Inmunología Clínica, Departamento de Inmunología, Escuela Nacional de Ciencias Biológicas, México.
Ethel García LatorreLaboratorio de Inmunología Clínica, Departamento de Inmunología, Escuela Nacional de Ciencias Biológicas, México.
Federico Centeno CruzLaboratorio de Inmunología-Genómica y Enfermedades Metabólicas, INMEGEN, Ciudad de México, México.
Adolfo Martínez TovarLaboratorio de Biología Molecular, Servicio de Hematología, Hospital General de México, Dr. Eduardo Liceaga, Ciudad de México Molecular Biology Laboratory, Ciudad de México, México.
Hospital General de México · MXNational Institute of Genomic Medicine · MXUniversidad Veracruzana · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Leukemia is a neoplasm with high incidence and mortality rates. Mitotic death has been observed in tumor cells treated with chemotherapeutic agents. Ras family proteins participate in the transduction of signals involved in different processes, such as proliferation, differentiation, survival, and paradoxically, initiation of cell death. Methods: This study investigated the effect of Results: Human T-cell acute lymphoblastic leukemia MOLT-4 cells showed nuclear fragmentation and presence of multiple nuclei and micronuclei after transfection with either wt or mutant Conclusion: Transfection of human T-cell acute lymphoblastic leukemia MOLT-4 cells with either normal or mutated

Indexed as

Mitotic catastropheMOLT-4RasS-phase arrest

Identifiers

PMID36632684
PMCPMC10063590
OpenAlexW4315651397

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.