ArticlePhotoacoustics2023
LED-based photoacoustic imaging for preoperative visualization of lymphatic vessels in patients with secondary limb lymphedema.
Article in Photoacoustics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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17 citing papers in PubMed, 27 citations in OpenAlex.
- Advanced methods of wearable ultrasound and photoacoustic imaging devices: A review.Photoacoustics · 2026Article
- Optimization of light source parameters for photoacoustic imaging: trade-offs, technologies, and clinical considerations.JPhys photonics · 2026Review
- 1064 nm-absorbing semiconducting polymer nanoparticles for multimodal photoacoustic and fluorescence imaging.Biomedical optics express · 2026Article
- [Research progress of photoacoustic imaging in diagnosis of limb lymphedema].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2026Review
- Efficient algorithm for optimal wavelength selection in photoacoustic spectral unmixing.Biomedical optics express · 2026Article
- Cutaneous lymphatics and skin diseases: mechanisms, imaging modalities, and future therapeutic strategies.Frontiers in physiology · 2026Review
- Radiomics-driven perfusion prediction in clinical photoacoustic foot imaging.Photoacoustics · 2025Article
- Laser Ultrasound Super-Resolution Imaging for Multi-Parametric Non-Invasive Volumetric Characterization of Brain Cancer.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Clinical translation of photoacoustic imaging using exogenous molecular contrast agents [Invited].Biomedical optics express · 2025Review
- Dual-wavelength photoacoustic imaging of sentinel lymph nodes in patients with melanoma and breast cancer.Photoacoustics · 2025Article
- Performance characterization of light-emitting diode array-based photoacoustic computed tomography (LED-PACT).Biomedical optics express · 2025Article
- Cost-Effective Photoacoustic Imaging Using High-Power Light-Emitting Diodes Driven by an Avalanche Oscillator.Sensors (Basel, Switzerland) · 2025Article
- Article
- Near-infrared multispectral photoacoustic analysis of lipids and intraplaque hemorrhage in human carotid artery atherosclerosis.Photoacoustics · 2024Article
- Photoacoustic imaging plus X: a review.Journal of biomedical optics · 2024Review
- Photoacoustic imaging on its way toward clinical utility: a tutorial review focusing on practical application in medicine.Journal of biomedical optics · 2023Review
- A review of a strategic roadmapping exercise to advance clinical translation of photoacoustic imaging: From current barriers to future adoption.Photoacoustics · 2023Review
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Lymphedema is the accumulation of protein-rich fluid in the interstitium (i.e., dermal backflow (DBF)). Preoperative imaging of the lymphatic vessels is a prerequisite for lymphovenous bypass surgical planning. We investigated the visualization of lymphatic vessels and veins using light-emitting diode (LED)-based photoacoustic imaging (PAI). Indocyanine-green mediated near-infrared fluorescence lymphography (NIRF-L) was done in fifteen patients with secondary limb lymphedema. Photoacoustic images were acquired in locations where lymphatic vessels and DBF were observed with NIRF-L. We demonstrated that LED-based PAI can visualize and differentiate lymphatic vessels and veins even in the presence of DBF. We observed lymphatic and blood vessels up to depths of 8.3 and 8.6 mm, respectively. Superficial lymphatic vessels and veins can be visualized using LED-based PAI even in the presence of DBF showing the potential for pre-operative assessment. Further development of the technique is needed to improve its usability in clinical settings.
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