Evidence map›Paper›PMID 36632585›Full record

ReviewCancer diagnosis & prognosis

The Landscape of Single Nucleotide Polymorphisms in Papillary Thyroid Carcinoma.

Efthymios Kyrodimos, Aristeidis Chrysovergis, Nicholas Mastronikolis, George Papanastasiou, Evangelos Tsiambas, Despoina Spyropoulou, Spyros Katsinis, Arezina Manoli, Sotirios Papouliakos, Pavlos Pantos and 3 more

Open access · greenAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Cancer diagnosis & prognosis. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. International journal of molecular sciences · 2025
    Article
  2. Polymorphisms of DNA Repair Genes in Thyroid Cancer.International journal of molecular sciences · 2024
    Review
  3. Article
  4. The Role of NQO1 in Ovarian Cancer.International journal of molecular sciences · 2023
    Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 1 country.

Efthymios KyrodimosFirst ENT Department, Hippocration Hospital, University of Athens, Athens, Greece.
Aristeidis ChrysovergisFirst ENT Department, Hippocration Hospital, University of Athens, Athens, Greece.
Nicholas MastronikolisENT Department, Medical School, University of Patras, Patras, Greece.
George PapanastasiouDepartment of Maxillofacial, Medical School, University of Ioannina, Ioannina, Greece.
Evangelos TsiambasDepartment of Cytology, 417 Veterans Army Hospital (NIMTS), Athens, Greece.
Despoina SpyropoulouDepartment of Radiation Oncology, Medical School, University of Patras, Patras, Greece.
Spyros KatsinisDepartment of Otorhinolaryngology, Thoracic Diseases General Hospital Sotiria, Athens, Greece.
Arezina ManoliDepartment of Otorhinolaryngology, Thoracic Diseases General Hospital Sotiria, Athens, Greece.
Sotirios PapouliakosDepartment of Otolaryngology, GNA Hospital Gennimatas, Athens, Greece.
Pavlos PantosFirst ENT Department, Hippocration Hospital, University of Athens, Athens, Greece.
Vasileios RagosDepartment of Maxillofacial, Medical School, University of Ioannina, Ioannina, Greece.
Dimitrios PeschosDepartment of Physiology, Medical School, University of Ioannina, Ioannina, Greece.
Vasileios PapanikolaouFirst ENT Department, Hippocration Hospital, University of Athens, Athens, Greece.
Hippocration General Hospital · GRUniversity of Ioannina · GRUniversity of Patras · GRNIMTS Hospital · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Thyroid carcinoma represents a leading malignancy among those derived from human endocrine systems. It comprises a variety of different histological subtypes, including mainly papillary carcinoma, follicular carcinoma, anaplastic carcinoma, and medullar carcinoma. A broad spectrum of genetic imbalances, comprising gross chromosomal (polysomy/aneuploidy) and specific gene (mutations, amplifications, deletions) alterations, has been reported. Interestingly, the role of isolated, specific gene polymorphisms, especially of the single nucleotide polymorphism (SNP) type, in thyroid carcinoma is under investigation. SNPs are the most common genetic variations in the genome. The current molecular review focuses on the impact of specific SNPs on the biological behavior of papillary thyroid carcinoma in their carriers.

Indexed as

carcinomaDNAgenereviewsingle nucleotide polymorphismsThyroid

Identifiers

PMID36632585
PMCPMC9801452
OpenAlexW4313364227

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.