Evidence map›Paper›PMID 36632577›Full record

ArticleJournal of hematology2022

Bone Involvement as a Primary Rare Manifestation of Waldenstrom Macroglobulinemia: A Case Report and Prevalence in a Nationwide Population-Based Cohort Study.

Khazra Bhatti, Aqsa Nazir, Simon Ostergaard, Lone Schejbel, Peter Norgaard, Lise M R Gjerdrum, Mahnaz Moghaddas, Torsten H Nielsen, Lars Munksgaard, Lars M Pedersen

Open access · hybridAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of hematology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. The performance and applied value ofAmerican journal of nuclear medicine and molecular imaging · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Khazra BhattiInstitute of Science and Environment, Roskilde University, Roskilde, Denmark.
Aqsa NazirInstitute of Science and Environment, Roskilde University, Roskilde, Denmark.
Simon OstergaardDepartment of Pathology, Zealand University Hospital, Roskilde, Denmark.
Lone SchejbelDepartment of Pathology, Herlev University Hospital, Herlev, Denmark.
Peter NorgaardDepartment of Pathology, Herlev University Hospital, Herlev, Denmark.
Lise M R GjerdrumDepartment of Pathology, Zealand University Hospital, Roskilde, Denmark.
Mahnaz MoghaddasDepartment of Radiology, Herlev University Hospital, Herlev, Denmark.
Torsten H NielsenDepartment of Hematology, Copenhagen University Hospital, Copenhagen, Denmark.
Lars MunksgaardDepartment of Hematology, Zealand University Hospital, Roskilde, Denmark.
Lars M PedersenDepartment of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.
Herlev Hospital · DKRoskilde University · DKUniversity of Copenhagen · DKZealand University Hospital · DKCopenhagen University Hospital · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bone involvement is a rare extranodal manifestation in patients with malignant lymphoproliferative diseases and has also been noted as a rare event in patients with Waldenstrom macroglobulinemia (WM). However, the actual prevalence has not been previously reported. We describe an unusual case of a patient with WM who presented with lower back pain and focal bone lesions at initial diagnosis. Magnetic resonance imaging (MRI) revealed multiple vertebral fractures. Positron emission tomography (PET) detected only nodal changes without pathological skeletal-related metabolic activity. Lymph node and bone marrow biopsies combined with an immunoglobulin M (IgM) M component revealed the diagnosis of WM. A next-generation sequencing (NGS) analysis using a targeted lymphoma panel of 59 recurrently mutated genes in lymphoid neoplasms showed mutations in the

Indexed as

B-cell lymphomaBone involvementBone lesionsExtramedullary diseaseLymphoplasmacytic lymphomaWaldenstrom macroglobulinemia

Identifiers

PMID36632577
PMCPMC9822657
OpenAlexW4313521367

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.