ReviewCurrent opinion in endocrine and metabolic research2022
Mathematical modelling of the oxytocin and vasopressin secretory system.
Review in Current opinion in endocrine and metabolic research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Abstract
Magnocellular oxytocin and vasopressin neurons of the hypothalamus project to the posterior pituitary where they secrete their peptide hormone signals directly into the bloodstream. Their large anatomically distinct secretory mechanisms provide a uniquely accessible system in which to unite experimental and modelling approaches in the investigation of how input signals and electrophysiological properties of neurons relate to physiological function. We describe how the mechanisms have been translated and assembled into a mathematical model representation that can explain and simulate the complex and highly non-linear stimulus-secretion coupling of these neurons, and how this model has been applied to further understand these systems.
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