ArticleTheranostics2023
FAM3C in circulating tumor-derived extracellular vesicles promotes non-small cell lung cancer growth in secondary sites.
Open access · goldAbstract read
In one paragraph
Article in Theranostics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
5.7field-weighted citation impact, top 3% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.
- Tumor Extracellular Vesicles Aggravate Mitochondrial Damage in Myocardial Ischemia/Reperfusion Injury.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Pooled it
- Extracellular vesicles from bronchoalveolar lavage fluid provide insights into the inhaled corticosteroids treatment response in COPD.Respiratory research · 2025Trial
- Artificial intelligence-based diagnostic model for identifying PTPRZ1-MET fusion in a clinically defined secondary glioblastoma cohort.Molecular biomedicine · 2026Article
- Exosome-mediated siRNA delivery in cancer: Loading strategies, targeting approaches, and therapeutic outcomes.Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences · 2026Review
- Extracellular vesicles in solid tumors: from tumor ecology to engineered therapeutics.Molecular cancer · 2026Review
- Cancer stem cells synthesize proline to attenuate oxidative stress.The Journal of clinical investigation · 2026Article
- Fam3C alters Golgi apparatus morphology and function in triple negative breast cancer.Journal of molecular cell biology · 2026Article
- Refining Lung Cancer Brain Metastasis Models for Spatiotemporal Dynamic Research and Personalized Therapy.Cancers · 2025Review
- Identification of a Biomarker Panel in Extracellular Vesicles Derived From Non-Small Cell Lung Cancer (NSCLC) Through Proteomic Analysis and Machine Learning.Journal of extracellular vesicles · 2025Article
- Stage-dependent proteomic alterations in aqueous humor of diabetic retinopathy patients based on data-independent acquisition and parallel reaction monitoring.Journal of translational medicine · 2025Article
- Cancer-induced systemic pre-conditioning of distant organs: building a niche for metastatic cells.Nature reviews. Cancer · 2024Review
- FAM3C Regulates Glioma Cell Proliferation, Invasion, Apoptosis, and Epithelial Mesenchymal Transition via the Notch Pathway.Cancer medicine · 2024Article
- Harmonising cellular conversations: decoding the vital roles of extracellular vesicles in respiratory system intercellular communications.European respiratory review : an official journal of the European Respiratory Society · 2024Review
- Immunogenomic features of radiologically distinctive nodules in multiple primary lung cancer.Cancer immunology, immunotherapy : CII · 2024Article
- Recent advances to address challenges in extracellular vesicle-based applications for lung cancer.Acta pharmaceutica Sinica. B · 2024Review
- Extracellular Vesicles in Lung Cancer: Implementation in Diagnosis and Therapeutic Perspectives.Cancers · 2024Review
- Unraveling the Connection: Extracellular Vesicles and Non-Small Cell Lung Cancer.International journal of nanomedicine · 2024Review
- Identification of exosome protein panels as predictive biomarkers for non-small cell lung cancer.Biological procedures online · 2023Article
- Single-cell characterization of self-renewing primary trophoblast organoids as modeling of EVT differentiation and interactions with decidual natural killer cells.BMC genomics · 2023Article
- An integrated bioinformatic analysis of bulk and single-cell sequencing clarifies immune microenvironment and metabolic profiles of lung adenocarcinoma to predict immunotherapy efficacy.Frontiers in cell and developmental biology · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
26 authors at 4 institutions in 3 countries.
Win Lwin ThuyaCancer Science Institute of Singapore, National University of Singapore, Singapore 117599.
Li Ren KongCancer Science Institute of Singapore, National University of Singapore, Singapore 117599.
Nicholas L SynCancer Science Institute of Singapore, National University of Singapore, Singapore 117599.
Ling-Wen DingCancer Science Institute of Singapore, National University of Singapore, Singapore 117599.
Esther Sok Hwee CheowCancer Science Institute of Singapore, National University of Singapore, Singapore 117599.
Regina Tong Xin WongCancer Science Institute of Singapore, National University of Singapore, Singapore 117599.
Tingting WangCancer Science Institute of Singapore, National University of Singapore, Singapore 117599.
Robby Miguel Wen-Jing GohCancer Science Institute of Singapore, National University of Singapore, Singapore 117599.
Hongyan SongCancer Science Institute of Singapore, National University of Singapore, Singapore 117599.
Migara K JayasingheDepartment of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
Minh Tn LeDepartment of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
Jian Cheng HuNUS Centre for Cancer Research (N2CR), Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
Wei-Peng YongCancer Science Institute of Singapore, National University of Singapore, Singapore 117599.
Soo-Chin LeeCancer Science Institute of Singapore, National University of Singapore, Singapore 117599.
Andrea Li-Ann WongCancer Science Institute of Singapore, National University of Singapore, Singapore 117599.
Gautam SethiDepartment of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
Huynh The HungDivision of Cellular and Molecular Research, National Cancer Centre, Singapore.
Paul Chi-Lui HoDepartment of Pharmacy, Faculty of Science, National University of Singapore, Singapore.
Jean-Paul ThieryCancer Science Institute of Singapore, National University of Singapore, Singapore 117599.
Siu Kwan SzeNanyang Technological University, 60 Nanyang Drive, Singapore 637551, Singapore.
Tiannan GuoZhejiang Provincial Laboratory of Life Sciences and Biomedicine, Key Laboratory of Structural Biology of Zhejiang Province, School of Life Sciences, Westlake University, China.
Ross A SooCancer Science Institute of Singapore, National University of Singapore, Singapore 117599.
Henry YangCancer Science Institute of Singapore, National University of Singapore, Singapore 117599.
Yaw Chyn LimCancer Science Institute of Singapore, National University of Singapore, Singapore 117599.
Lingzhi WangCancer Science Institute of Singapore, National University of Singapore, Singapore 117599.
Boon-Cher GohCancer Science Institute of Singapore, National University of Singapore, Singapore 117599.
National University Cancer Institute, Singapore · SGNational University of Singapore · SGInstitute of Basic Medical Sciences of the Chinese Academy of Medical SciencesNational Cancer Centre Singapore · SG
Funding
No grant is acknowledged in the PubMed record.
Abstract
PubMed holds no abstract for this paper.
Indexed as
CarcinogenesisCarcinoma, Non-Small-Cell LungExtracellular VesiclesLung NeoplasmsAnimalsCell Line, TumorCytokinesHumansMiceNeoplasm ProteinsProteomicsCytokinesFAM3C protein, humanFam3c protein, mouseNeoplasm ProteinsFAM3Cnon-small cell lung carcinomapredictive biomarkertumor-derived extracellular vesiclestumor metastasis.
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.