Evidence map›Paper›PMID 36632192›Full record

ArticleExpert review of ophthalmology2022

Hyalocyte origin, structure, and imaging.

Peter Wieghofer, Michael Engelbert, Toco Yp Chui, Richard B Rosen, Taiji Sakamoto, J Sebag

Open access · hybridAbstract read
In one paragraph

Article in Expert review of ophthalmology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Hyalocytes-guardians of the vitreoretinal interface.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2024
    Review
  7. Article
  8. Article
  9. Macrophage activation contributes to diabetic retinopathy.Journal of molecular medicine (Berlin, Germany) · 2024
    Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Hyalocytes in proliferative vitreo-retinal diseases.Expert review of ophthalmology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 3 countries.

Peter WieghoferCellular Neuroanatomy, Institute of Theoretical Medicine, Medical Faculty, University of Augsburg, Universitätsstraße 2, 86159 Augsburg, Germany.
Michael EngelbertVitreous Retina Macula Consultants of New York, New York, NY 10022, USA.
Toco Yp ChuiDepartment of Ophthalmology, New York Eye and Ear Infirmary of Mount Sinai, New York, New York; Department of Ophthalmology, Icahn School of Medicine at Mount Sinai, New York, New York.
Richard B RosenDepartment of Ophthalmology, New York Eye and Ear Infirmary of Mount Sinai, New York, New York; Department of Ophthalmology, Icahn School of Medicine at Mount Sinai, New York, New York.
Taiji SakamotoDepartment of Ophthalmology, Kagoshima University Graduate School of Medical and Dental Science, Kagoshima, Japan.
J SebagDoheny Eye Institute, UCLA, Los Angeles, CA, USA.
Icahn School of Medicine at Mount Sinai · USDoheny Eye Institute · USKagoshima University · JPManhattan Eye, Ear and Throat Hospital · USUniversity of Augsburg · DE

Funding

SCD REVIVE - Retina to Evaluate Vaso occlusion In the Vasculature of the EyeR01HL159116 · NHLBI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Yuen Ping Toco Chui, Jeffrey Avins Glassberg · 2022 to 2026
$4.0M
Characterization of vascular responses to intravitreal anti-VEGF injections in diabetic retinopathyR01EY027301 · NEI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Yuen Ping Toco Chui · 2017 to 2026
$4.0M
NEI NIH HHS R01 EY027301NHLBI NIH HHS R01 HL159116
6 · The paper itself

Abstract

Introduction: Hyalocytes have been recognized as resident tissue macrophages of the vitreous body since the mid-19 Areas covered: Historically, initial studies on the origin of hyalocytes used light and electron microscopy. Modern investigations across species including rodents and humans will be described. Novel imaging is now available to study human hyalocytes Expert opinion: Owing to a common origin as myeloid cells, hyalocytes and retinal microglia have similarities, but hyalocytes appear to be distinct as resident macrophages of the vitreous body.

Indexed as

HyalocytesImagingMacrophagesMonocytesOriginTurnoverVitreous

Identifiers

PMID36632192
PMCPMC9831111
OpenAlexW4296703712

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.