Evidence map›Paper›PMID 36632186›Full record

ArticleBrain communications2023

Sleep slow-wave oscillations trigger seizures in a genetic epilepsy model of Dravet syndrome.

Mackenzie A Catron, Rachel K Howe, Gai-Linn K Besing, Emily K St John, Cobie Victoria Potesta, Martin J Gallagher, Robert L Macdonald, Chengwen Zhou

Open access · goldAbstract read
In one paragraph

Article in Brain communications, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Mackenzie A CatronDepartment of Neurology, Vanderbilt University Medical Center, Nashville, TN 37232, USA.
Rachel K HoweDepartment of Neurology, Vanderbilt University Medical Center, Nashville, TN 37232, USA.
Gai-Linn K BesingDepartment of Neurology, Vanderbilt University Medical Center, Nashville, TN 37232, USA.
Emily K St JohnDepartment of Neurology, Vanderbilt University Medical Center, Nashville, TN 37232, USA.
Cobie Victoria PotestaDepartment of Neurology, Vanderbilt University Medical Center, Nashville, TN 37232, USA.
Martin J GallagherDepartment of Neurology, Vanderbilt University Medical Center, Nashville, TN 37232, USA.
Robert L MacdonaldDepartment of Neurology, Vanderbilt University Medical Center, Nashville, TN 37232, USA.
Chengwen ZhouDepartment of Neurology, Vanderbilt University Medical Center, Nashville, TN 37232, USA.ORCID https://orcid.org/0000-0002-0222-1515
Vanderbilt University Medical Center · US

Funding

Overall: Eunice Kennedy Shriver Intellectual and Developmental Disabilities Research Center at VanderbiltP50HD103537 · NICHD · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Jeffrey L Neul · 2020 to 2026
$10.3M
Subcortical Nodes Within Epileptic Network Control the Cortical Disfacilitation to Prompt Seizure Onset in IGE Mouse ModelR01NS107424 · NINDS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI ZHOU, CHENGWEN · 2018 to 2022
$2.0M
NICHD NIH HHS P50 HD103537NINDS NIH HHS R01 NS107424
6 · The paper itself

Abstract

Sleep is the preferential period when epileptic spike-wave discharges appear in human epileptic patients, including genetic epileptic seizures such as Dravet syndrome with multiple mutations including SCN1A mutation and GABA

Indexed as

Dravet syndromegenetic epilepsysleepslow-wave oscillationsspike–wave discharges

Identifiers

PMID36632186
PMCPMC9830548
OpenAlexW4313354141

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.