Evidence map›Paper›PMID 36632182›Full record

ArticleBrain communications2023

White-matter abnormalities in presymptomatic

Hyunwoo Lee, Ian R A Mackenzie, Mirza Faisal Beg, Karteek Popuri, Rosa Rademakers, Dana Wittenberg, Ging-Yuek Robin Hsiung

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Brain communications, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 4 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 3 countries.

Hyunwoo LeeDivision of Neurology, Department of Medicine, University of British Columbia, Vancouver V6T2B5, Canada.ORCID https://orcid.org/0000-0002-8598-9123
Ian R A MackenzieDepartment of Pathology and Laboratory Medicine, Faculty of Medicine, University of British Columbia, Vancouver V6T2B5, Canada.
Mirza Faisal BegSchool of Engineering Science, Simon Fraser University, Burnaby V5A1S6, Canada.
Karteek PopuriDepartment of Computer Science, Memorial University of Newfoundland, St John's A1B3X5, Canada.
Rosa RademakersApplied and Translational Neurogenomics, VIB Center for Molecular Neurology, VIB, Antwerp 2610, Belgium.
Dana WittenbergDivision of Neurology, Department of Medicine, University of British Columbia, Vancouver V6T2B5, Canada.
Ging-Yuek Robin HsiungDivision of Neurology, Department of Medicine, University of British Columbia, Vancouver V6T2B5, Canada.
University of British Columbia · CAMemorial University of Newfoundland · CASimon Fraser University · CAUniversity of Antwerp · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A large proportion of familial frontotemporal dementia is caused by TAR DNA-binding protein 43 (transactive response DNA-binding protein 43 kDa) proteinopathies. Accordingly, carriers of autosomal dominant mutations in the genes associated with TAR DNA-binding protein 43 aggregation, such as Chromosome 9 open reading frame 72 (

Indexed as

frontotemporal dementiaMRIwhite matter

Identifiers

PMID36632182
PMCPMC9825756
OpenAlexW4313422585

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.