Evidence map›Paper›PMID 36632056›Full record

ReviewClinical and translational radiation oncology2023

Adaptive radiotherapy for breast cancer.

C De-Colle, A Kirby, N Russell, S F Shaitelman, A Currey, E Donovan, E Hahn, K Han, C N Anandadas, F Mahmood and 7 more

Open access · goldAbstract readReview
In one paragraph

Review in Clinical and translational radiation oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Experience and uncertainty analysis of CT-based adaptive radiotherapy for abdominal treatments.Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB) · 2025
    Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 13 institutions in 6 countries.

C De-ColleDepartment of Radiation Oncology, University Hospital and Medical Faculty, Eberhard Karls University Tübingen, Tübingen, Germany.
A KirbyDepartment of Radiotherapy, Royal Marsden NHS Foundation Trust and Institute of Cancer Research, Sutton, United Kingdom.
N RussellDepartment of Radiotherapy, The Netherlands Cancer Institute-Antoni van Leeuwenhoek Hospital, Amsterdam, Netherlands.
S F ShaitelmanDepartment of Radiation Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, United States.
A CurreyDepartment of Radiation Oncology, Medical College of Wisconsin, Milwaukee, WI, United States.
E DonovanDepartment of Radiation Oncology, Odette Cancer Centre - Sunnybrook Health Sciences Centre, Toronto, Canada.
E HahnDepartment of Radiation Oncology, Princess Margaret Cancer Centre, Toronto, Canada.
K HanDepartment of Radiation Oncology, Princess Margaret Cancer Centre, Toronto, Canada.
C N AnandadasDepartment of Clinical Oncology, The Christie NHS Foundation Trust, Manchester, United Kingdom.
F MahmoodDepartment of Oncology, Odense University Hospital, Odense, Denmark.
E L LorenzenDepartment of Oncology, Odense University Hospital, Odense, Denmark.
D van den BongardDepartment of Radiation Oncology, Amsterdam UMC, Amsterdam, Netherlands.
M L Groot KoerkampDepartment of Radiation Oncology, University Medical Center Utrecht, Utrecht, Netherlands.
A C HouwelingDepartment of Radiation Oncology, University Medical Center Utrecht, Utrecht, Netherlands.
M NachbarSection for Biomedical Physics, Department of Radiation Oncology. University Hospital and Medical Faculty, Eberhard Karls University Tübingen, Tübingen, Germany.
D ThorwarthSection for Biomedical Physics, Department of Radiation Oncology. University Hospital and Medical Faculty, Eberhard Karls University Tübingen, Tübingen, Germany.
D ZipsDepartment of Radiation Oncology, University Hospital and Medical Faculty, Eberhard Karls University Tübingen, Tübingen, Germany.
Odense University Hospital · DKPrincess Margaret Cancer Centre · CAUniversity Medical Center Utrecht · NLUniversity of Tübingen · DEAmsterdam University Medical Centers · NLDeutschen Konsortium für Translationale Krebsforschung · DEGerman Cancer Research Center · DEHealth Sciences Centre · CAInstitute of Cancer Research · GBMedical College of Wisconsin · USThe Christie NHS Foundation Trust · GBThe Netherlands Cancer Institute · NLThe University of Texas MD Anderson Cancer Center · US

Funding

Cancer Research UK 28284
6 · The paper itself

Abstract

Research in the field of local and locoregional breast cancer radiotherapy aims to maintain excellent oncological outcomes while reducing treatment-related toxicity. Adaptive radiotherapy (ART) considers variations in target and organs at risk (OARs) anatomy occurring during the treatment course and integrates these in re-optimized treatment plans. Exploiting ART routinely in clinic may result in smaller target volumes and better OAR sparing, which may lead to reduction of acute as well as late toxicities. In this review MR-guided and CT-guided ART for breast cancer patients according to different clinical scenarios (neoadjuvant and adjuvant partial breast irradiation, whole breast, chest wall and regional nodal irradiation) are reviewed and their advantages as well as challenging aspects discussed.

Indexed as

Adaptive radiotherapyBreast cancerMR-linacPartial breast irradiation

Identifiers

PMID36632056
PMCPMC9826896
OpenAlexW4313530564

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.