Evidence map›Paper›PMID 36631882›Full record

ArticleEuropean journal of medical research2023

Prediction of survival time after terminal extubation: the balance between critical care unit utilization and hospice medicine in the COVID-19 pandemic era.

Yun-Cong Zheng, Yen-Min Huang, Pin-Yuan Chen, Hsiao-Yean Chiu, Huang-Pin Wu, Chien-Ming Chu, Wei-Siang Chen, Yu-Cheng Kao, Ching-Fang Lai, Ning-Yi Shih and 1 more

Open access · goldAbstract read
In one paragraph

Article in European journal of medical research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Palliative extubation in intensive care units: scoping review.Revista da Escola de Enfermagem da U S P · 2026
    Article
  2. How Long Do We Have? A Retrospective Review of Palliative Extubation in the Burn Unit.Journal of burn care & research : official publication of the American Burn Association · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 1 country.

Yun-Cong ZhengDepartments of Neurosurgery, Chang Gung Memorial Hospital, Keelung and Linkou & Chang Gung University, Taoyuan, Taiwan.
Yen-Min HuangDivision of Hematology-Oncology, Department of Internal Medicine, Chang Gung Memorial Hospital, No. 222, Maijin Rd., Anle Dist., Keelung, 204, Taiwan.
Pin-Yuan ChenDepartments of Neurosurgery, Chang Gung Memorial Hospital, Keelung and Linkou & Chang Gung University, Taoyuan, Taiwan.
Hsiao-Yean ChiuSchool of Nursing, College of Nursing, Taipei Medical University, Taipei, Taiwan.
Huang-Pin WuDivision of Pulmonary, Critical Care and Sleep Medicine, Chang Gung Memorial Hospital, Keelung, 20401, Taiwan.
Chien-Ming ChuDivision of Pulmonary, Critical Care and Sleep Medicine, Chang Gung Memorial Hospital, Keelung, 20401, Taiwan.
Wei-Siang ChenDivision of Cardiology Section, Internal Medicine, Chang Gung Memorial Hospital, Keelung & Chang Gung University, Taoyuan, Taiwan.
Yu-Cheng KaoDivision of Cardiology Section, Internal Medicine, Chang Gung Memorial Hospital, Keelung & Chang Gung University, Taoyuan, Taiwan.
Ching-Fang LaiDepartment of Social Services, Chang Gung Memorial Hospital, Keelung, Taiwan.
Ning-Yi ShihDivision of Hematology-Oncology, Department of Internal Medicine, Chang Gung Memorial Hospital, No. 222, Maijin Rd., Anle Dist., Keelung, 204, Taiwan.
Chien-Hong LaiDivision of Hematology-Oncology, Department of Internal Medicine, Chang Gung Memorial Hospital, No. 222, Maijin Rd., Anle Dist., Keelung, 204, Taiwan. october99pub@gmail.com.
Chang Gung Memorial Hospital · TWChang Gung University · TWChung Shan Medical University · TWKeelung Chang Gung Memorial Hospital · TWLinkou Chang Gung Memorial Hospital · TWTaipei Medical University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe established 1-h and 1-day survival models after terminal extubation to optimize ventilator use and achieve a balance between critical care for COVID-19 and hospice medicine.

methodsData were obtained from patients with end-of-life status at terminal extubation from 2015 to 2020. The associations between APACHE II scores and parameters with survival time were analyzed. Parameters with a p-value ≤ 0.2 in univariate analysis were included in multivariate models. Cox proportional hazards regression analysis was used for the multivariate analysis of survival time at 1 h and 1 day.

resultsOf the 140 enrolled patients, 76 (54.3%) died within 1 h and 35 (25%) survived beyond 24 h. No spontaneous breathing trial (SBT) within the past 24 h, minute ventilation (MV) ≥ 12 L/min, and APACHE II score ≥ 25 were associated with shorter survival in the 1 h regression model. Lower MV, SpO2 ≥ 96% and SBT were related to longer survival in the 1-day model. Hospice medications did not influence survival time.

conclusionAn APACHE II score of ≥ 25 at 1 h and SpO2 ≥ 96% at 1 day were strong predictors of disposition of patients to intensivists. These factors can help to objectively tailor pathways for post-extubation transition and rapidly allocate intensive care unit resources without sacrificing the quality of palliative care in the era of COVID-19. Trial registration They study was retrospectively registered. IRB No.: 202101929B0.

Indexed as

COVID-19HospicesAirway ExtubationCritical CareHumansIntensive Care UnitsPandemicsRespiration, ArtificialAPACHE II scoreCOVID-19Hospice medicineIntensive care unitSpO2Terminal extubation

Identifiers

PMID36631882
PMCPMC9832251
OpenAlexW4315650497

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.