Evidence map›Paper›PMID 36631821›Full record

ArticleImplementation science : IS2023

Factors influencing postpartum haemorrhage detection and management and the implementation of a new postpartum haemorrhage care bundle (E-MOTIVE) in Kenya, Nigeria, and South Africa.

Gillian Forbes, Shahinoor Akter, Suellen Miller, Hadiza Galadanci, Zahida Qureshi, Sue Fawcus, G Justus Hofmeyr, Neil Moran, Mandisa Singata-Madliki, Faisal Dankishiya and 11 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Implementation science : IS, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04341662 (Early Detection of Postpartum Haemorrhage and Treatment Using the World Health Organisation MOTIVE 'First Response' Bundle), which is not on this map. Cited by 28 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 2 pooled it
13.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04341662 nacompletednot on this map

Early Detection of Postpartum Haemorrhage and Treatment Using the World Health Organisation MOTIVE 'First Response' Bundle: a Cluster Randomised Trial With Health Economic Analysis and Mixed-methods Evaluation (E-MOTIVE Trial)

TypeinterventionalSponsorUniversity of BirminghamRan2020 to 2023Enrolled99,659ConditionsPost-Partum HaemorrhageArmsE-MOTIVE intervention, Usual care
3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 2 syntheses or guidelines pooled it, 40 citations in OpenAlex.

  1. Pooled it
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  6. From guesstimates to game changers: Introducing objective measurement of blood loss for timely postpartum hemorrhage detection in Nigeria, Zambia, and Kenya.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2026
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  14. FIGO call to action: Multisectoral approach to postpartum hemorrhage.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 11 institutions in 8 countries.

Gillian ForbesCentre for Behaviour Change, University College London, London, UK. g.forbes@ucl.ac.uk.
Shahinoor AkterGender and Women's Health Unit, Centre for Health Equity, University of Melbourne School of Population and Global Health, 207 Bouverie St, Carlton, Victoria, 3053, Australia.
Suellen MillerDepartment of Obstetrics, Gynaecology, and Reproductive Sciences, School of Medicine, University of California, San Francisco, USA.
Hadiza GaladanciAfrica Center of Excellence for Population Health and Policy, Bayero University Kano, Kano, Nigeria.
Zahida QureshiDepartment of Obstetrics and Gynaecology, University of Nairobi, Nairobi, Kenya.
Sue FawcusDepartment of Obstetrics and Gynaecology, University of Cape Town, Cape Town, South Africa.
G Justus HofmeyrDepartment of Obstetrics and Gynaecology, University of Botswana, Gaborone, Botswana.
Neil MoranKwaZulu-Natal Department of Health, University of KwaZulu-Natal, Durban, South Africa.
Mandisa Singata-MadlikiEffective Care Research Unit, Department of Obstetrics and Gynaecology, Universities of Witwatersrand and Fort Hare, East London, South Africa.
Faisal DankishiyaAfrica Center of Excellence for Population Health and Policy, Bayero University Kano and Department of Community Medicine, Bayero University/Aminu Kano Teaching Hospital, Kano, Nigeria.
George GwakoDepartment of Obstetrics and Gynaecology, University of Nairobi, Nairobi, Kenya.
Alfred OsotiDepartment of Obstetrics and Gynaecology, University of Nairobi, Nairobi, Kenya.
Eleanor ThomasTommy's National Centre for Miscarriage Research, Institute of Metabolism and Systems Research (IMSR), WHO Collaborating Centre for Global Women's Health Research, University of Birmingham, Mendelsohn Way, Edgbaston, Birmingham, UK.
Ioannis GallosWHO Collaborating Centre on Global Women's Health, Institute of Metabolism and Systems Research, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.
Kristie-Marie MammolitiWHO Collaborating Centre on Global Women's Health, Institute of Metabolism and Systems Research, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.
Adam DevallWHO Collaborating Centre on Global Women's Health, Institute of Metabolism and Systems Research, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.
Arri CoomarasamyWHO Collaborating Centre on Global Women's Health, Institute of Metabolism and Systems Research, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.
Fernando AlthabeDepartment of Sexual and Reproductive Health and Research, World Health Organization, UNDP/UNFPA/UNICEF/WHO/World Bank Special Programme of Research, Development and Research Training in Human Reproduction (HRP), Geneva, Switzerland.
Lou AtkinsCentre for Behaviour Change, University College London, London, UK.
Meghan A BohrenGender and Women's Health Unit, Centre for Health Equity, University of Melbourne School of Population and Global Health, 207 Bouverie St, Carlton, Victoria, 3053, Australia.
Fabiana LorencattoCentre for Behaviour Change, University College London, London, UK.
University of Birmingham · GBUniversity College London · GBUniversity of Nairobi · KEBayero University Kano · NGUniversity of Melbourne · AUMiscarriage Association · GBUniversity of California, San Francisco · USUniversity of Cape Town · ZAUniversity of KwaZulu-Natal · ZAUniversity of the Witwatersrand · ZAWorld Health Organization · CH

Funding

Medical Research Council MR/T038985/1World Health Organization 001
6 · The paper itself

Abstract

backgroundPostpartum haemorrhage (PPH) is the leading cause of global maternal deaths, accounting for 30-50% of maternal deaths in sub-Saharan Africa. Most PPH-related deaths are preventable with timely detection and initiation of care, which may be facilitated by using a clinical care bundle. We explore influences on current PPH detection and management and on the future implementation of a new PPH bundle (E-MOTIVE) in low-resource, high-burden settings.

methodsSemi-structured qualitative interviews based on the Theoretical Domains Framework were conducted with 45 healthcare providers across nine hospitals in Nigeria, Kenya and South Africa, to identify barriers and enablers to current PPH detection and management and future implementation of a new PPH care bundle. Data were analysed using thematic and framework analysis. The Behaviour Change Wheel was used to identify potential interventions to address identified barriers and enablers.

resultsInfluences on current PPH detection and management fell under 12 domains: Environmental Context and Resources (drug and staff shortages), Skills (limited in-service training), Knowledge (variable understanding of the recommended practice), Behaviour Regulation (limited quality improvement culture), Beliefs about Consequences (drawbacks from inaccurate detection), Emotion (stress from the unpredictability of PPH), Social Influence (teamwork), Memory, Attention and Decision-making (limited guideline use), Social/Professional Role and Identity (role clarity), Beliefs about Capabilities (confidence in managing PPH), Reinforcement (disciplinary procedures) and Goals (PPH as a priority). Influences on bundle uptake included: Beliefs about Consequences (perceived benefits of new blood loss measurement tool), Environmental Context and Resources (high cost of drugs and new tools), Memory, Attention and Decision-making (concerns about whether bundle fits current practice), Knowledge (not understanding 'bundled' approach), Social Influence (acceptance by women and staff) and Intention (limited acceptance of 'bundled' approach over existing practice). These influences were consistent across countries. Proposed interventions included: Education, Training, Modelling (core and new skills), Enablement (monitoring uptake), Persuasion (leadership role) and Environmental Restructuring (PPH emergency trolley/kit).

conclusionsA wide range of individual, socio-cultural and environmental barriers and enablers to improving PPH detection and management exist in these settings. We identified a range of interventions that could improve PPH care and the implementation of new care bundles in this context.

trial registrationClinicalTrials.gov : NCT04341662.

Indexed as

Maternal DeathPatient Care BundlesPostpartum HemorrhageFemaleHumansKenyaNigeriaSouth AfricaBehaviour Change WheelClinical care bundleFormative researchImplementation interventionsLow- and middle-income countries (LMICs)Maternal healthPostpartum haemorrhage (PPH)Qualitative interviews

Identifiers

PMID36631821
PMCPMC9832403
OpenAlexW4315573220

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.