ArticleImplementation science : IS2023
Factors influencing postpartum haemorrhage detection and management and the implementation of a new postpartum haemorrhage care bundle (E-MOTIVE) in Kenya, Nigeria, and South Africa.
Article in Implementation science : IS, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04341662 (Early Detection of Postpartum Haemorrhage and Treatment Using the World Health Organisation MOTIVE 'First Response' Bundle), which is not on this map. Cited by 28 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Early Detection of Postpartum Haemorrhage and Treatment Using the World Health Organisation MOTIVE 'First Response' Bundle: a Cluster Randomised Trial With Health Economic Analysis and Mixed-methods Evaluation (E-MOTIVE Trial)
Who cites it
28 citing papers in PubMed, 2 syntheses or guidelines pooled it, 40 citations in OpenAlex.
- Barriers and facilitators to the implementation of integrated disease surveillance and response (IDSR) in Africa: a systematic review using the consolidated framework for implementation research (CFIR).Frontiers in public health · 2026Pooled it
- Clinical and healthcare systems-level interventions for postpartum hemorrhage prevention and management in Nigeria: a systematic review of effectiveness and implementation outcomes.Frontiers in health services · 2026Pooled it
- Early detection and a treatment bundle strategy for postpartum haemorrhage: a mixed-methods process evaluation.The Lancet. Global health · 2025Trial
- A cost-effectiveness analysis of early detection and bundled treatment of postpartum hemorrhage alongside the E-MOTIVE trial.Nature medicine · 2024Trial
- Prevalence, characteristics, and outcomes of postpartum hemorrhage in a tertiary hospital in Tigray, Northern Ethiopia (2017-2021): retrospective descriptive study.BMC pregnancy and childbirth · 2026Article
- From guesstimates to game changers: Introducing objective measurement of blood loss for timely postpartum hemorrhage detection in Nigeria, Zambia, and Kenya.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2026Article
- Factors influencing implementation of an Alzheimer's disease blood test among UK old age psychiatrists: mixed-methods study using the theoretical domains framework.Age and ageing · 2026Article
- Feasibility, acceptability, and effectiveness of the E-MOTIVE bundle intervention for early detection and management of postpartum hemorrhage in a low-middle-income country: implementation research.AJOG global reports · 2026Article
- Healthcare Workers' Perspectives on the E-MOTIVE Postpartum Haemorrhage Bundle in Tanzania: A Qualitative Study of Implementation Facilitators and Challenges.International journal of women's health · 2026Article
- Introducing the E-MOTIVE Bundle for the Management of Postpartum Hemorrhage: Perceptions of Health Professionals and Perceived Barriers to Its Implementation in Sub-Saharan Africa.Journal of pregnancy · 2026Article
- Disparities in maternal and fetal health among ethnogeographic groups-a retrospective cohort study of 30,000 women from a middle eastern multiethnic maternity population.Frontiers in global women's health · 2026Article
- Scaling up implementation of the E-MOTIVE bundle for early detection and management of postpartum haemorrhage emergencies: A scoping review.Health SA = SA Gesondheid · 2026Review
- Management practices of primary postpartum hemorrhage among traditional birth attendants: a qualitative survey, Iganga, Uganda.African health sciences · 2025Article
- FIGO call to action: Multisectoral approach to postpartum hemorrhage.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2025Article
- Optimizing Availability and Appropriate Use of Assisted Vaginal Birth: Protocol for Generic Formative Research of an Implementation Preparation.JMIR research protocols · 2025Article
- Using Theory-Based Frameworks to Identify Barriers and Enablers of Physicians' Telemedicine Adoption and Develop Intervention Strategies in China: Multicenter Qualitative Study.Journal of medical Internet research · 2025Article
- Factors Influencing Pregnant Women's Participation in Randomised Clinical Trials in India: A Qualitative Study.BJOG : an international journal of obstetrics and gynaecology · 2025Article
- Barriers and facilitators influencing midwives' implementation of South Africa's maternal care guidelines in postnatal health: a scoping review.Primary health care research & development · 2025Article
- Avoidable factors associated with maternal death from postpartum haemorrhage: a national Malawian surveillance study.BMJ global health · 2025Article
- Heat-Stable Carbetocin in the Management of Postpartum Haemorrhage in Low- and Middle-Income Countries: A Comprehensive Review of Clinical Evidence, Cost-Effectiveness, Implementation Challenges and Adoption Strategies.International journal of women's health · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
21 authors at 11 institutions in 8 countries.
Funding
Abstract
backgroundPostpartum haemorrhage (PPH) is the leading cause of global maternal deaths, accounting for 30-50% of maternal deaths in sub-Saharan Africa. Most PPH-related deaths are preventable with timely detection and initiation of care, which may be facilitated by using a clinical care bundle. We explore influences on current PPH detection and management and on the future implementation of a new PPH bundle (E-MOTIVE) in low-resource, high-burden settings.
methodsSemi-structured qualitative interviews based on the Theoretical Domains Framework were conducted with 45 healthcare providers across nine hospitals in Nigeria, Kenya and South Africa, to identify barriers and enablers to current PPH detection and management and future implementation of a new PPH care bundle. Data were analysed using thematic and framework analysis. The Behaviour Change Wheel was used to identify potential interventions to address identified barriers and enablers.
resultsInfluences on current PPH detection and management fell under 12 domains: Environmental Context and Resources (drug and staff shortages), Skills (limited in-service training), Knowledge (variable understanding of the recommended practice), Behaviour Regulation (limited quality improvement culture), Beliefs about Consequences (drawbacks from inaccurate detection), Emotion (stress from the unpredictability of PPH), Social Influence (teamwork), Memory, Attention and Decision-making (limited guideline use), Social/Professional Role and Identity (role clarity), Beliefs about Capabilities (confidence in managing PPH), Reinforcement (disciplinary procedures) and Goals (PPH as a priority). Influences on bundle uptake included: Beliefs about Consequences (perceived benefits of new blood loss measurement tool), Environmental Context and Resources (high cost of drugs and new tools), Memory, Attention and Decision-making (concerns about whether bundle fits current practice), Knowledge (not understanding 'bundled' approach), Social Influence (acceptance by women and staff) and Intention (limited acceptance of 'bundled' approach over existing practice). These influences were consistent across countries. Proposed interventions included: Education, Training, Modelling (core and new skills), Enablement (monitoring uptake), Persuasion (leadership role) and Environmental Restructuring (PPH emergency trolley/kit).
conclusionsA wide range of individual, socio-cultural and environmental barriers and enablers to improving PPH detection and management exist in these settings. We identified a range of interventions that could improve PPH care and the implementation of new care bundles in this context.
trial registrationClinicalTrials.gov : NCT04341662.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.