ArticleBMC psychiatry2023
Interaction of anxiety and hypertension on quality of life among patients with gynecological cancer: a cross-sectional study.
Article in BMC psychiatry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 13 citations in OpenAlex.
- Cancer Survivorship After COVID-19: Psychological Burden, Symptom Experience, and Social Support.Medicina (Kaunas, Lithuania) · 2026Article
- The Impact of Rosenthal Effect-Based Psychological Nursing on Psychological State, Self-Efficacy, and Quality of Life in Patients Undergoing Total Hysterectomy for Uterine Fibroids: A Randomized Controlled Trial.International journal of women's health · 2026Article
- The relationship between cognitive function and quality of life in older hypertension patients: a parallel mediation effect of frailty and medication discrepancies.BMC geriatrics · 2025Article
- Exploring Patient-Centered Perspectives on Suicidal Ideation: A Mixed-Methods Investigation in Gastrointestinal Cancer Care.Cancers · 2025Article
- Impact of anxiety and chemotherapy side effects on quality of life in patients with malignant lymphoma.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025Observational
- Perceived Social Support and Health-Related Quality of Life Among Hypertensive Patients: A Latent Profile Analysis and the Role of Delay Discounting and Living Alone.Risk management and healthcare policy · 2024Article
- Sense of coherence mediates perceived social support and depressive and anxiety symptoms in cervical cancer patients: a cross-sectional study.BMC psychiatry · 2023Article
- Understanding the Quality of Life Among Patients With Cancer in Saudi Arabia: Insights From a Cross-Sectional Study.Cancer control : journal of the Moffitt Cancer CenterArticle
- Quality of Life and Predictors among Gastrointestinal Cancer Survivors in Iran.Iranian journal of nursing and midwifery researchArticle
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4 authors at 1 institution in 1 country.
Funding
Abstract
backgroundPatients with gynecological cancer are prone to anxiety, and many of them are accompanied by hypertension, which seriously affects the quality of life (QOL). The study was to explore the interaction of anxiety and hypertension on QOL, and the moderating effect of perceived social support (PSS) in the impact of anxiety and hypertension on QOL of patients with gynecological cancer.
methodsA cross-sectional study was conducted in 2020, and 566 patients have been collected from the Affiliated Hospital of China Medical University. The Self-Rating Anxiety Scale (SAS), the Functional Assessment of Cancer Therapy Genera tool (FACT-G), and the Multidimensional Scale of Perceived Social Support Scale (MSPSS) were used. The interaction was analyzed by additive model, and the moderating effect was conducted by regression analysis and the simple slope analysis.
resultsWe found that 68.8% of patients had poor QOL due to the interaction between anxiety and hypertension. The relative excess risk ratio (RERI) was 22.238 (95%CI:44.119-88.596); the attribution ratio (AP) was 0.688 (95%CI:0.234-1.142); The interaction index (S) was 3.466 (95%CI: 0.823-14.435). The interaction items of PSS and anxiety were negatively correlated with QOL (β = -0.219, P < 0.01) and explained an additional 4.0% variance (F = 68.649, Adjusted R
conclusionsWhen anxiety and hypertension coexist, the QOL was affected. PSS played a moderating role in the impact of anxiety on QOL. Healthcare providers should take intervention measures to improve patients' social support to reduce the impact of anxiety on QOL.
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