ArticleBMC surgery2023
Risk factor analysis and prediction of postoperative clinically relevant pancreatic fistula after distal pancreatectomy.
Article in BMC surgery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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15 citing papers in PubMed, 18 citations in OpenAlex.
- Transpapillary pancreatic duct stenting as a salvage therapy for refractory pancreatic fistula after distal pancreatectomy: a case series supporting the role of duodenal papilla obstruction.Surgical endoscopy · 2026Article
- Correlation between inflammation, vascularization, adipocyte percentage and exocrine cell percentage at the resection margin and the postoperative pancreatic fistula rate after distal pancreatectomy.Langenbeck's archives of surgery · 2026Article
- Is Kangduo robotic distal pancreatectomy more economically efficient and effective in postoperative outcomes compared to laparoscopic surgery? A propensity-matched analysis.Journal of robotic surgery · 2025Article
- Developing a predictive model for healing of clinically relevant pancreatic fistulas post-pancreatoduodenectomy based on clinical and imaging nutritional status.Japanese journal of radiology · 2025Article
- Integrative deep learning analysis of 2D and 3D body composition features for predicting postoperative pancreatic fistula after distal pancreatectomy.Annals of medicine · 2025Article
- Developing and validating a nomogram to forecast clinically relevant postoperative pancreatic fistula following distal pancreatectomy.Gland surgery · 2025Article
- Retrospective investigation of risk factors for pancreatic fistula development after pancreaticoduodenectomy.World journal of gastrointestinal surgery · 2025Article
- Postoperative outcomes and their risk factors in left pancreatectomy with and without multivisceral resection.Scientific reports · 2025Article
- Risk prediction and clinical utility analysis of postoperative pancreatic fistula: a comparative study of multivariable logistic regression and random forest models.Frontiers in surgery · 2025Article
- Application of 3D Printing to Design and Manufacture Pancreatic Duct Stent and Animal Experiments.Bioengineering (Basel, Switzerland) · 2024Article
- Perioperative pancreaticoduodenectomy management strategy focusing on postoperative early drain colonization.Surgery today · 2024Article
- Identifying the risk factors for pancreatic fistula after laparoscopic pancreaticoduodenectomy in patients with pancreatic cancer.World journal of gastrointestinal surgery · 2024Article
- Optimizing prediction models for pancreatic fistula after pancreatectomy: Current status and future perspectives.World journal of gastroenterology · 2024Review
- Simple Preoperative Imaging Measurements Predict Postoperative Pancreatic Fistula After Pancreatoduodenectomy.Annals of surgical oncology · 2024Article
- Hepatobiliary anastomotic leakage: a narrative review of definitions, grading systems, and consequences of leaks.Translational gastroenterology and hepatology · 2024Review
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
objectivePostoperative pancreatic fistula (POPF) following distal pancreatectomy (DP) is a serious complication. In the present study, we aimed to identify the risk factors associated with clinically relevant postoperative pancreatic fistula (CR-POPF) and establish a nomogram model for predicting CR-POPF after DP.
methodsIn total, 115 patients who underwent DP at the General Hospital of Northern Theater Command between January 2005 and December 2020 were retrospectively studied. Univariate and multivariable logistic regression analyses were used to identify the independent risk factors associated with CR-POPF. Then, a nomogram was formulated based on the results of multivariable logistic regression analysis. The predictive performance was evaluated with receiver operating characteristic (ROC) curves. Decision curve and clinical impact curve analyses were used to validate the clinical application value of the model.
resultsThe incidence of CR-POPF was 33.0% (38/115) in the present study. Multivariate logistic regression analysis identified the following variables as independent risk factors for POPF: body mass index (BMI) (OR 4.658, P = 0.004), preoperative albumin level (OR 7.934, P = 0.001), pancreatic thickness (OR 1.256, P = 0.003) and pancreatic texture (OR 3.143, P = 0.021). We created a nomogram by incorporating the above mentioned risk factors. The nomogram model showed better predictive value, with a concordance index of 0.842, sensitivity of 0.710, and specificity of 0.870 when compared to each risk factor. Decision curve and clinical impact curve analyses also indicated that the nomogram conferred a high clinical net benefit.
conclusionOur nomogram could accurately and objectively predict the risk of postoperative CR-POPF in individuals who underwent DP, which could help clinicians with early identification of patients who might develop CR-POPF and early development of a suitable fistula mitigation strategy and postoperative management.
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